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双侧卵巢无性细胞瘤的治疗及11年随访:一例报告

Treatment of bilateral ovarian dysgerminoma with 11-year follow-up: A case report.

作者信息

Zogbi Luciano, Gonçalves Carla Vitola, Tejada Victor Felipe, Martins Daiane, Karam Fabine, Machado Dos Santos Sílvia, Caldeira Roberta Raseira, Senhorin Gisele Zanetti, Lauz Susi

机构信息

Faculdade de Medicina (FAMED) - Universidade Federal do Rio Grande (FURG), Rio Grande city, Rio Grande do Sul State, Brazil.

出版信息

Ann Med Surg (Lond). 2018 Aug 21;33:50-52. doi: 10.1016/j.amsu.2018.08.009. eCollection 2018 Sep.

Abstract

INTRODUCTION

Malignant ovarian germ cell tumors (MOGCTs) are rare malignancies with an incidence of about 0.5/100,000. They account for less than 5% of all ovarian tumors, of which 32.8% are dysgerminomas, the female analogue of seminomas. These tumors occur in all age groups, with peak incidence below the age of 20 years in women.

AIM

To describe the case of a bilateral ovarian dysgerminoma treatment with 11-year follow-up.

METHODS

Case report with details regarding clinical history, surgical treatment, chemotherapy and follow up. We include a brief literature review.

RESULTS

The patient underwent radical surgery for an advanced dysgerminoma, 20 cm in length, that compromised the contralateral ovary and sigmoid. Neoplastic cells were found in ascitic fluid. Subsequently, she underwent adjuvant chemotherapy according to a standard protocol. She has survived disease-free for more than 11 years.

CONCLUSIONS

Dysgerminoma is a malignant neoplasm that, similar to other cancers, is easier to treat when diagnosed early. However, cures may be obtained even in advanced cases.

摘要

引言

恶性卵巢生殖细胞肿瘤(MOGCTs)是罕见的恶性肿瘤,发病率约为0.5/10万。它们占所有卵巢肿瘤的比例不到5%,其中32.8%为无性细胞瘤,是精原细胞瘤的女性对应物。这些肿瘤可发生于所有年龄组,女性发病高峰年龄在20岁以下。

目的

描述一例双侧卵巢无性细胞瘤的治疗情况并进行11年随访。

方法

病例报告,包括临床病史、手术治疗、化疗及随访的详细信息。我们还进行了简要的文献综述。

结果

患者因晚期无性细胞瘤接受了根治性手术,肿瘤长20厘米,累及对侧卵巢和乙状结肠。腹水液中发现了肿瘤细胞。随后,她按照标准方案接受了辅助化疗。她已无病生存超过11年。

结论

无性细胞瘤是一种恶性肿瘤,与其他癌症一样,早期诊断时更容易治疗。然而,即使在晚期病例中也可能实现治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61f7/6122391/297e94015f38/gr1.jpg

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