Zogbi Luciano, Isaías Angélica, Machado Pedro Augusto, Neutzling Aluísio, Juliano Camila
Faculdade de Medicina (FAMED) - Universidade Federal do Rio Grande (FURG), Rio Grande City, Rio Grande do Sul State, Brazil.
Faculdade de Medicina (FAMED) - Universidade Federal do Rio Grande (FURG), Rio Grande City, Rio Grande do Sul State, Brazil.
Int J Surg Case Rep. 2017;41:184-187. doi: 10.1016/j.ijscr.2017.10.029. Epub 2017 Nov 5.
Krukenberg tumour (KT) is defined by the World Health Organization as a metastatic ovary carcinoma, usually of gastric origin. The term has also been applied to metastatic tumors originating from adenocarcinomas of other sites, such as the colon. After radical resection of colorectal carcinoma, metachronous ovarian metastases can occur in 1.1% of cases. Due to their rarity and rapid progression, KTs needs a high level of suspicion. Here we present an atypical case of KT and highlight the importance of the timely recognition of this disease.
A 57-year-old patient presented a 30-cm metastatic ovarian tumor on the major axis, whose primary tumor was a resected sigmoid adenocarcinoma 6 years ago. She was submitted to complete resection of the tumor, whose anatomopathological and immunohistochemical analysis proved the colonic metastatic origin.
Besides being unusual, this disease is most commonly bilateral, premenopausal, and synchronous with the primary tumor. Unlike the common behavior, the case described is unilateral, postmenopausal, and metachronous, with a 6-year interval between the primary colonic tumor and the dissemination of ovarian metastasis.
KT is an uncommon and poor prognosis disease, whose chance of better therapeutic results depends on accurate diagnosis and proper management.
世界卫生组织将库肯勃瘤（KT）定义为转移性卵巢癌，通常起源于胃。该术语也适用于源自其他部位腺癌（如结肠）的转移性肿瘤。在结直肠癌根治性切除术后，异时性卵巢转移的发生率为1.1%。由于其罕见性和快速进展，库肯勃瘤需要高度怀疑。在此，我们报告一例非典型库肯勃瘤病例，并强调及时识别该疾病的重要性。
一名57岁患者出现一个长径为30 cm的转移性卵巢肿瘤，其原发肿瘤为6年前切除的乙状结肠腺癌。她接受了肿瘤的完整切除，其解剖病理学和免疫组织化学分析证实了结肠转移来源。
除了不常见外，这种疾病最常见的是双侧、绝经前且与原发肿瘤同时发生。与常见情况不同，所描述的病例是单侧、绝经后且异时性的，原发性结肠肿瘤与卵巢转移扩散之间间隔6年。
库肯勃瘤是一种罕见且预后不良的疾病，其获得更好治疗效果的机会取决于准确的诊断和恰当的处理。
