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二氧化铪在生物传感器中的应用。

Use of hafnium(IV) oxide in biosensors.

作者信息

Ortiz-Dosal Luis Carlos, Ángeles-Robles Gabriela, Kolosovas-Machuca Eleazar Samuel

机构信息

a Doctorado Institucional en Ingeniería y Ciencia de Materiales (DICIM-UASLP) , Universidad Autónoma de San Luis Potosí , San Luis Potosí , México.

b Posgrado en Ciencias Interdisciplinarias, Instituto de Física , Universidad Autónoma de San Luis Potosí , San Luis Potosí , México.

出版信息

J Immunoassay Immunochem. 2018;39(5):471-484. doi: 10.1080/15321819.2018.1517090. Epub 2018 Sep 6.

Abstract

Hafnium(IV) oxide is a material with properties that can increase the sensitivity, durability, and reliability of biosensors made from silicon dioxide and other semiconductor materials due to its high dielectric constant, thermodynamic stability, and the simplicity with which it can be deposited. This work describes the use of this material in biosensors based on field-effect transistors to detect ions and DNA, in immunosensors to detect an antigen-antibody complex, its use as a contrast material in computed tomography scans and the possibility of using it in optic biosensors in the infrared region. Its low cost and versatility in the field of biosensors is underscored.

摘要

二氧化铪是一种材料,由于其高介电常数、热力学稳定性以及易于沉积的特性,能够提高由二氧化硅和其他半导体材料制成的生物传感器的灵敏度、耐用性和可靠性。这项工作描述了这种材料在基于场效应晶体管的生物传感器中用于检测离子和DNA,在免疫传感器中用于检测抗原 - 抗体复合物,在计算机断层扫描中用作对比材料以及在红外区域的光学生物传感器中使用的可能性。强调了其在生物传感器领域的低成本和多功能性。

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