Neven Adriana Catharina Helena, Laven Joop, Teede Helena J, Boyle Jacqueline A
Department of Obstetrics and Gynecology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Monash Centre for Health Research and Implementation, Monash Public Health and Preventive Medicine, Monash University, Clayton, Victoria, Australia.
Semin Reprod Med. 2018 Jan;36(1):5-12. doi: 10.1055/s-0038-1668085. Epub 2018 Sep 6.
Polycystic ovary syndrome (PCOS) is a common hormonal condition with reproductive, metabolic, and psychological sequelae. The Rotterdam Criteria are now internationally accepted, with different phenotypes recognized with varying clinical presentations and risk profiles. The complexity of the disorder, and the impact on quality of life, requires timely diagnosis, screening for complications and management strategies. PCOS remains underdiagnosed and women experience significant delays to diagnosis. Effective dissemination of evidence-based management is therefore vital. In this review, we summarize key aspects of PCOS as a prelude to this issue of on PCOS which focuses on the development of the international evidence-based guideline on the assessment and management of PCOS and the related translation program. We cover diagnostic criteria, prevalence, phenotypes, reproductive, metabolic, and psychological factors of PCOS. We also cover management strategies including lifestyle interventions as well as treatment of nonreproductive outcomes and reproductive outcomes informed by the latest international evidence-based guidelines.
多囊卵巢综合征（PCOS）是一种常见的激素紊乱疾病，会导致生殖、代谢和心理方面的后遗症。鹿特丹标准目前已被国际认可，不同的表型具有不同的临床表现和风险特征。该疾病的复杂性以及对生活质量的影响，需要及时诊断、筛查并发症并制定管理策略。PCOS仍然诊断不足，女性患者在诊断上会经历显著延迟。因此，有效传播基于证据的管理方法至关重要。在本综述中，我们总结了PCOS的关键要点，作为本期关于PCOS特刊的前奏，该特刊重点关注PCOS评估和管理的国际循证指南的制定以及相关翻译项目。我们涵盖了PCOS的诊断标准、患病率、表型、生殖、代谢和心理因素。我们还介绍了管理策略，包括生活方式干预以及根据最新国际循证指南对非生殖结局和生殖结局的治疗。
