Macias A, Azavedo E, Perez R, Rutqvist L E, Skoog L
Anticancer Res. 1986 Jul-Aug;6(4):849-51.
The tumor cell content of the receptor for epidermal growth factor (EGF-R) and estrogen receptor (ER) was analyzed in 36 primary breast carcinomas and their metastatic deposits. Twenty-five percent of the primary tumors and 48 percent of the metastases exhibited measurable levels of the receptor. The frequency of EGF-R positivity was the same for cutaneous and lymph node recurrences. No discrepancy was observed with respect to ER content between primary tumors and their metastases.
对36例原发性乳腺癌及其转移灶的表皮生长因子受体（EGF-R）和雌激素受体（ER）的肿瘤细胞含量进行了分析。25%的原发性肿瘤和48%的转移灶显示出可检测水平的受体。皮肤复发和淋巴结复发的EGF-R阳性频率相同。原发性肿瘤及其转移灶在ER含量方面未观察到差异。
