Menard H A, Dion J, Richard C
J Rheumatol. 1977 Spring;4(1):21-6.
The phytohemagglutinin induced response of lymphocytes was studied in two groups of rheumatoid patients differing only in the presence or absence of antinuclear antibodies (ANA). The response was found to be depressed in 16 ANA positive and normal in 14 ANA negative patients. Antinuclear antibody screening may serve as a simple method to identify a subgroup of immunodepressed rheumatoid patients who may be potential candidates for immunostimulation therapy.
在两组仅抗核抗体（ANA）呈阳性或阴性不同的类风湿患者中，研究了植物血凝素诱导的淋巴细胞反应。结果发现，16例ANA阳性患者的反应受到抑制，14例ANA阴性患者的反应正常。抗核抗体筛查可作为一种简单的方法，用以识别免疫功能低下的类风湿患者亚组，这些患者可能是免疫刺激疗法的潜在候选者。
