Balda M S, Pirola C J, Dabsys S M, Finkielman S, Nahmod V E
Clin Exp Hypertens A. 1986;8(6):997-1008. doi: 10.3109/10641968609044082.
A low molecular weight substance which behaves like ouabain as inhibitor of brain membrane Na-K-ATPase and 3H-ouabain binding was found in plasma after saline expansion of extracellular fluid or angiotensin II infusion into the third brain ventricle in the rat. Intracerebroventricular infusion of angiotensin II antagonist, saralasin, blocks the increase of the Na-K-ATPase inhibitor produced by infusion of angiotensin II into the third ventricle or extracellular fluid saline expansion.
在给大鼠细胞外液扩容生理盐水或向第三脑室注入血管紧张素II后，在血浆中发现了一种低分子量物质，其作为脑细胞膜钠钾ATP酶抑制剂和3H-哇巴因结合物的作用与哇巴因相似。脑室内注入血管紧张素II拮抗剂沙拉新，可阻断因向第三脑室注入血管紧张素II或细胞外液扩容生理盐水而导致的钠钾ATP酶抑制剂增加。
