Sammartano L J, Tuveson R W, Davenport R
J Bacteriol. 1986 Oct;168(1):13-21. doi: 10.1128/jb.168.1.13-21.1986.
Mutations in the Escherichia coli katF gene (hydroperoxidase II) result in sensitivity to inactivation by H2O2 and broad-spectrum near-UV (NUV; 300 to 400 nm) radiation. Another mutation, nur, originally described as conferring sensitivity to inactivation by broad-spectrum and monochromatic NUV, also confers sensitivity to inactivation by H2O2. Genetic analysis via transduction suggests that the nur mutation allele of the katF locus. As previously reported for broad-spectrum and monochromatic NUV wavelengths, the sensitivity of a particular strain to H2O2 inactivation is also independent of the recA and uvrA alleles. Extracts of nur and katF strains lack catalase (hydroperoxidase II) as revealed by polyacrylamide gels stained for such activity, which is consistent with the genetic results.
大肠杆菌katF基因（过氧化氢酶II）的突变会导致对H2O2失活以及广谱近紫外（NUV；300至400nm）辐射敏感。另一个突变nur，最初被描述为赋予对广谱和单色NUV失活的敏感性，也赋予对H2O2失活的敏感性。通过转导进行的遗传分析表明，nur突变是katF基因座的等位基因。如先前关于广谱和单色NUV波长的报道，特定菌株对H2O2失活的敏感性也与recA和uvrA等位基因无关。经对此类活性进行染色的聚丙烯酰胺凝胶显示，nur和katF菌株的提取物缺乏过氧化氢酶（过氧化氢酶II），这与遗传结果一致。
