Cano-Jiménez Esteban, Hernández González Fernanda, Peloche Guadalupe Bermudo
Hospital Universitario Lucus Augusti, Respiratory Department, 27002 Lugo, Spain.
Hospital Clínic, Respiratory Department, 08036 Barcelona, Spain.
Med Sci (Basel). 2018 Aug 30;6(3):71. doi: 10.3390/medsci6030071.
Though idiopathic pulmonary fibrosis (IPF) is characterized by single-organ involvement, many comorbid conditions occur within other organ systems. Patients with IPF may present during evolution different complications and comorbidities that influence the prognosis and modify the natural course of their disease. In this chapter, we highlight common comorbid conditions encountered in IPF, discuss disease-specific diagnostic modalities, and review the current treatment data for several key comorbidities. The diagnosis and treatment of these comorbidities is a challenge for the pulmonologist specialized in interstitial lung diseases (ILDs). We will focus on pulmonary emphysema, lung cancer, gastroesophageal reflux, pulmonary hypertension, obstructive sleep apnea (sleep disorders), and acute exacerbation of IPF.
尽管特发性肺纤维化（IPF）以单一器官受累为特征，但其他器官系统中也会出现许多合并症。IPF患者在疾病进展过程中可能出现不同的并发症和合并症，这些会影响预后并改变疾病的自然进程。在本章中，我们重点介绍IPF中常见的合并症，讨论特定疾病的诊断方法，并回顾几种关键合并症的当前治疗数据。对于专门研究间质性肺病（ILDs）的肺科医生而言，这些合并症的诊断和治疗是一项挑战。我们将重点关注肺气肿、肺癌、胃食管反流、肺动脉高压、阻塞性睡眠呼吸暂停（睡眠障碍）以及IPF急性加重。
