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蔬菜蛋白对高胆固醇血症和肠道微生物群调节的影响。

Effects of Vegetable Proteins on Hypercholesterolemia and Gut Microbiota Modulation.

机构信息

Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milano, Italy.

Centro Dislipidemie, A.S.S.T. Grande Ospedale Metropolitano Niguarda, 220162 Milano, Italy.

出版信息

Nutrients. 2018 Sep 6;10(9):1249. doi: 10.3390/nu10091249.

DOI:10.3390/nu10091249
PMID:30200592
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6164761/
Abstract

Risk assessment tools, i.e., validated risk prediction algorithms, to estimate the patient's 10-year risk of developing cardiovascular disease (CVD) should be used to identify high-risk people for primary prevention. Current evidence confirms that appropriate monitoring and control of risk factors either reduces the likelihood of CVD or slows down its progression. It is thus crucial that all health professionals make appropriate use of all the available intervention strategies to control risk factors: from dietary improvement and adequate physical activity to the use of functional foods, food supplements, and drugs. The gut microbiota, which encompasses 1 × 10 resident microorganisms, has been recently recognized as a contributing factor in the development of human disease. This review examines the effect of both some vegetable food components belong to the "protein food group" and the underexploited protein-rich hempseed on cholesterolemia and gut microbiota composition.

摘要

风险评估工具,即经过验证的风险预测算法,用于估计患者发生心血管疾病(CVD)的 10 年风险,应用于识别高危人群进行一级预防。现有证据证实,适当监测和控制危险因素可以降低 CVD 的发生可能性或减缓其进展速度。因此,所有卫生专业人员都必须正确使用所有可用的干预策略来控制危险因素:从改善饮食和进行适当的身体活动到使用功能性食品、膳食补充剂和药物。肠道微生物群包含 1×10 个常驻微生物,最近被认为是人类疾病发展的一个促成因素。本综述研究了“蛋白质食物组”中的一些蔬菜食物成分和尚未充分利用的富含蛋白质的大麻籽对胆固醇血症和肠道微生物群组成的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a1/6164761/3486619e38e8/nutrients-10-01249-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a1/6164761/c39b78ffbaf7/nutrients-10-01249-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a1/6164761/3486619e38e8/nutrients-10-01249-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a1/6164761/c39b78ffbaf7/nutrients-10-01249-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a1/6164761/3486619e38e8/nutrients-10-01249-g002.jpg

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本文引用的文献

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Pharmacol Res. 2018 Aug;134:51-60. doi: 10.1016/j.phrs.2018.05.015. Epub 2018 May 30.
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