Chen Donglai, Fu Ranran, Shi Pingfan, Qin Shuang, Chen Chang
Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China.
Tongji University School of Medicine, Shanghai 200092, China.
Zhongguo Fei Ai Za Zhi. 2018 Sep 20;21(9):719-726. doi: 10.3779/j.issn.1009-3419.2018.09.12.
Intraoperative pleural lavage cytology is a diagnostic technique used to detect tumor cells and serve as a prognostic parameter for non-small cell lung cancer (NSCLC) patients. In the past several decades, many scholars have been dedicated to clarifying the relationships between positive intraoperative pleural lavage cytology results and postoperative survival as well as tumor recurrence and metastasis. However, the findings remained various due to the inhomogeneity of different research. It has been confirmed that a positive intraoperative pleural lavage cytology result is one of the risk factors for the prognosis of postoperative patients. This study reviewed the advances in research of intraoperative pleural lavage cytology in recent years from several aspects, including clinical significance, influencing factors and possible mechanisms. .
术中胸腔灌洗细胞学检查是一种用于检测肿瘤细胞并作为非小细胞肺癌（NSCLC）患者预后参数的诊断技术。在过去几十年中，许多学者致力于阐明术中胸腔灌洗细胞学检查阳性结果与术后生存以及肿瘤复发和转移之间的关系。然而，由于不同研究的异质性，研究结果仍然各不相同。已经证实，术中胸腔灌洗细胞学检查阳性结果是术后患者预后的危险因素之一。本研究从临床意义、影响因素和可能机制等几个方面综述了近年来术中胸腔灌洗细胞学检查的研究进展。
