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伴有小肾肿块的肾脏:在部分肾切除术时代,它们可用于肾移植吗?

Kidneys with small renal masses: Can they be utilized for kidney transplantation in the era of partial nephrectomy?

作者信息

Arpalı Emre, Günaydın Bilal, Turan Turgay, Çaşkurlu Turhan, Yıldırım Asıf, Koçak Burak

机构信息

Department of Organ Transplantation, Istanbul Memorial Hospital, İstanbul, Turkey.

Department of Urology, Istanbul Medeniyet University School of Medicine, İstanbul, Turkey.

出版信息

Turk J Urol. 2018 Nov;44(6):503-507. doi: 10.5152/tud.2018.89264.

Abstract

OBJECTIVE

To retrospectively evaluate our database to determine our partial nephrectomy and radical nephrectomy rates and to see percentage of the discarded kidneys which were suitable for transplantation after radical nephrectomy.

MATERIAL AND METHODS

Patients who underwent radical or partial nephrectomy between January 2000 and December 2016 were identified. Only stage I tumors according to tumor, node, metastasis classification were included in this review. Tumor size, location, proximity to renal collecting system and hilum were considered while deciding the suitability of a kidney for transplantation.

RESULTS

A statistically significant gradual increase in the number of patients treated with partial nephrectomy was observed (p=0.00001). Only 17 out of 181 kidneys with a tumor size smaller than 3 cm could be an appropriate candidate for a renal transplantation if they were to be transplanted.

CONCLUSION

Exact number of the discarded kidneys with small renal masses which can be used for kidney transplantation should be determined by large scale studies. A national or governmental policy may only be developed to utilize these discarded organs after the magnitude of the wasted kidneys can be determined.

摘要

目的

回顾性评估我们的数据库,以确定我们的部分肾切除术和根治性肾切除术的发生率,并了解根治性肾切除术后适合移植的废弃肾脏的百分比。

材料与方法

确定2000年1月至2016年12月期间接受根治性或部分肾切除术的患者。本综述仅纳入根据肿瘤、淋巴结、转移分类为I期的肿瘤。在决定肾脏是否适合移植时,考虑肿瘤大小、位置、与肾集合系统和肾门的接近程度。

结果

观察到接受部分肾切除术的患者数量有统计学意义的逐渐增加(p=0.00001)。如果要进行移植,181个肿瘤大小小于3 cm的肾脏中只有17个可能是肾移植的合适候选者。

结论

可用于肾移植的小肾肿块废弃肾脏的确切数量应由大规模研究确定。只有在确定了废弃肾脏的数量后,才可能制定国家或政府政策来利用这些废弃器官。

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