Department of Food Science & Biotechnology, Gachon University, Seongnam-si, Gyeonggi-do, 13120, Republic of Korea.
World J Microbiol Biotechnol. 2018 Sep 10;34(10):143. doi: 10.1007/s11274-018-2527-3.
Bacterial and fungal spore contamination in different industries has a greater economic impact. Because of the remarkable resistance of spores to most physical and chemical microbicidal agents, their inactivation need special attention during sterilization processes. Heat and chemical sporicides are not always well suited for different sterilization/decontamination applications and carries inherent risks. In recent years, novel nonthermal agents including nonthermal plasmas are emerging as effective sporicides against a broad spectrum of bacterial and fungal spores. The present review discusses various aspects related to the inactivation of spores using nonthermal plasmas. Different types of both low pressure plasmas (e.g., capacitively coupled plasma and microwave plasma) and atmospheric pressure plasmas (e.g., dielectric barrier discharges, corona discharges, arc discharges, radio-frequency-driven plasma jet) have been successfully applied to destroy spores of economic significance. Plasma agents contributing to sporicidal activity and their mode of action in inactivation are discussed. In addition, information on factors that affect the sporicidal action of nonthermal plasmas is included.
不同行业中的细菌和真菌孢子污染会造成更大的经济影响。由于孢子对大多数物理和化学杀菌剂具有显著的抗性，因此在灭菌过程中需要特别注意对其进行灭活。热和化学杀菌剂并不总是适用于不同的灭菌/消毒应用，并且存在固有风险。近年来，新型非热剂（包括非热等离子体）作为一种有效的杀菌剂，可针对广泛的细菌和真菌孢子发挥作用。本综述讨论了使用非热等离子体灭活孢子的各个方面。已经成功应用了各种类型的低压等离子体（例如，电容耦合等离子体和微波等离子体）和大气压等离子体（例如，介质阻挡放电、电晕放电、电弧放电、射频驱动等离子体射流）来破坏具有经济意义的孢子。讨论了对杀菌活性有贡献的等离子体试剂及其在失活过程中的作用方式。此外，还提供了影响非热等离子体杀菌作用的因素信息。
