Calvopina Manuel, Aguirre Cristina, Cevallos William, Castillo Alberto, Abbasi Ibrahim, Warburg Alon
Carrera de Medicina, Universidad De Las Americas (UDLA), Quito, Ecuador.
Servicio de Medicina Interna, Hospital Eugenio Espejo, Quito, Ecuador.
Am J Trop Med Hyg. 2017 May;96(5):1151-1154. doi: 10.4269/ajtmh.16-0431. Epub 2017 Feb 13.
AbstractReported herein is the first case of -human immunodeficiency virus (HIV) coinfection in Ecuador. In Ecuador, HIV infections overlap endemic areas of leishmaniasis. Immunosuppression is a well-established risk factor for developing severe disease. This is a severe case of a 32-year-old man presenting with disseminated pleomorphic ulcers, papules, and cutaneous plaque-like lesions over his whole body. Numerous amastigotes were observed in both skin scrapings and biopsies. The sequence of the gene confirmed the presence of . The patient was treated but failed to respond to meglumine antimoniate and amphotericin B. Six months later, the patient died due to bacterial septic shock.
摘要本文报道了厄瓜多尔首例人类免疫缺陷病毒（HIV）合并感染病例。在厄瓜多尔，HIV感染与利什曼病的流行地区重叠。免疫抑制是发生严重疾病的一个公认危险因素。这是一名32岁男性的严重病例，其全身出现弥漫性多形性溃疡、丘疹和皮肤斑块样病变。在皮肤刮片和活检组织中均观察到大量无鞭毛体。该基因的序列证实了 的存在。患者接受了治疗，但对葡甲胺锑酸盐和两性霉素B均无反应。6个月后，患者因细菌性败血症休克死亡。
