Vitale Cristiana, Spoletini Ilaria, Rosano Giuseppe Mc
Centre for Clinical and Basic Research, Department of Medical Sciences, IRCCS San Raffaele Pisana Rome, Italy.
Card Fail Rev. 2018 Aug;4(2):104-106. doi: 10.15420/cfr.2018.22.2.
Frailty is a complex clinical syndrome associated with ageing and chronic illness, resulting from multiple organ impairment; physiological reserves decrease and vulnerability to stressors increase. The role of frailty in cardiovascular disease has become increasingly recognised. Up to 79% of patients with heart failure are frail. Moreover, frailty is associated with a worse quality of life and poor prognosis. This review summarises the available literature on frailty in HF and highlights indications for its management.
衰弱是一种与衰老和慢性疾病相关的复杂临床综合征，由多器官功能损害引起；生理储备减少，对压力源的易感性增加。衰弱在心血管疾病中的作用已得到越来越多的认可。高达79%的心力衰竭患者存在衰弱。此外，衰弱与较差的生活质量和不良预后相关。本综述总结了关于心力衰竭中衰弱的现有文献，并强调了其管理的指征。
