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25年内将心力衰竭死亡率降低25%:“25 in 25”心力衰竭峰会

Reducing heart failure deaths by 25% in 25 years: the '25in25' heart failure summit.

作者信息

Beishon Lucy, Jayasinghe Rebecca, Roshan-Zamir Shahbaz, Barton Carys

机构信息

NIHR Academic Clinical Lecturer NIHR Leicester Biomedical Research Centre, BHF Cardiovascular Research Centre, Glenfield Hospital, Groby Road, Leicester, LE3 9QP.

Geriatrics and GIM Higher Specialty Trainee.

出版信息

Br J Cardiol. 2024 Jun 11;31(2):022. doi: 10.5837/bjc.2024.022. eCollection 2024.

DOI:10.5837/bjc.2024.022
PMID:39555464
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11562576/
Abstract

Heart failure (HF) is a major cause of morbidity and mortality in older people, and 80% of people with HF are aged over 60 years. HF is the end point for almost all common cardiovascular diseases, as well as many non-cardiovascular diseases. Despite this, HF remains underdetected and undertreated. Detection and treatment of HF has improved significantly in recent years, with several novel treatments developed in the last decade improving outcomes for patients. Therefore, earlier detection and improved treatment of HF has the potential to reduce morbidity and mortality for older people, particularly given the shift in ageing demographics anticipated over the coming decades. The British Geriatrics Society Cardiovascular Specialist Interest Group recently participated in the British Society for Heart Failure (BSH) '25in25' Heart Failure Summit, which aims to reduce deaths due to HF by 25% in the next 25 years. The 2023 summit comprised experts from over 45 top health organisations across Europe, Canada and the US. The summit brought together cross-disciplinary expertise to support the implementation of strategies to improve outcomes for people living with HF, and, in this commentary, we reflect upon the priorities identified. We discuss the current barriers to the early detection and management of HF, and the particular challenges and complexity of managing HF in older people. Finally, we discuss the role of patient empowerment and how this can lead to improved care for older people living with HF.

摘要

心力衰竭(HF)是老年人发病和死亡的主要原因,80%的心力衰竭患者年龄超过60岁。心力衰竭是几乎所有常见心血管疾病以及许多非心血管疾病的终点。尽管如此,心力衰竭的检测和治疗仍然不足。近年来,心力衰竭的检测和治疗有了显著改善,过去十年开发的几种新疗法改善了患者的预后。因此,早期检测和改善心力衰竭的治疗有可能降低老年人的发病率和死亡率,特别是考虑到未来几十年预期的人口老龄化趋势。英国老年医学会心血管专科兴趣小组最近参加了英国心力衰竭协会(BSH)的“25年内在25年内”心力衰竭峰会,该峰会旨在在未来25年内将心力衰竭导致的死亡人数减少25%。2023年的峰会汇聚了来自欧洲、加拿大和美国45多个顶级健康组织的专家。峰会汇集了跨学科专业知识,以支持实施改善心力衰竭患者预后的策略,在本评论中,我们反思了确定的优先事项。我们讨论了目前心力衰竭早期检测和管理的障碍,以及老年人管理心力衰竭的特殊挑战和复杂性。最后,我们讨论了患者赋权的作用以及这如何能够改善对老年心力衰竭患者的护理。

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Efficacy and Safety of Dapagliflozin According to Frailty in Patients With Heart Failure: A Prespecified Analysis of the DELIVER Trial.达格列净在心力衰竭患者中的疗效和安全性:DELIVER 试验的预先设定分析。
Circulation. 2022 Oct 18;146(16):1210-1224. doi: 10.1161/CIRCULATIONAHA.122.061754. Epub 2022 Aug 27.
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Frailty assessment in the management of cardiovascular disease.心血管疾病管理中的衰弱评估
Heart. 2022 Nov 24;108(24):1991-1995. doi: 10.1136/heartjnl-2022-321265.
3
Missed Opportunities in the Diagnosis of Heart Failure: Evaluation of Pathways to Determine Sources of Delay to Specialist Evaluation.心力衰竭诊断中的错失机会:评估导致延迟至专科评估的原因的途径。
Curr Heart Fail Rep. 2022 Aug;19(4):247-253. doi: 10.1007/s11897-022-00551-4. Epub 2022 Jun 6.
4
Frailty Status Modifies the Efficacy of Exercise Training Among Patients With Chronic Heart Failure and Reduced Ejection Fraction: An Analysis From the HF-ACTION Trial.虚弱状态改变了射血分数降低的慢性心力衰竭患者运动训练的疗效:HF-ACTION 试验的分析。
Circulation. 2022 Jul 12;146(2):80-90. doi: 10.1161/CIRCULATIONAHA.122.059983. Epub 2022 May 26.
5
Frailty and Post-hospitalization Outcomes in Patients With Heart Failure With Preserved Ejection Fraction.射血分数保留的心力衰竭患者的衰弱与院后结局
Am J Cardiol. 2021 Jun 1;148:84-93. doi: 10.1016/j.amjcard.2021.02.019. Epub 2021 Mar 3.
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The prevalence and importance of frailty in heart failure with reduced ejection fraction - an analysis of PARADIGM-HF and ATMOSPHERE.射血分数降低的心力衰竭中衰弱的流行和重要性——PARADIGM-HF 和 ATMOSPHERE 分析。
Eur J Heart Fail. 2020 Nov;22(11):2123-2133. doi: 10.1002/ejhf.1832. Epub 2020 Apr 30.
7
Mortality after hospital admission for heart failure: improvement over time, equally strong in women as in men.心力衰竭患者住院后的死亡率:随着时间的推移而改善,在女性和男性中同样明显。
BMC Public Health. 2020 Jan 10;20(1):36. doi: 10.1186/s12889-019-7934-3.
8
Frailty in patients with heart failure.心力衰竭患者的衰弱
Eur Heart J Suppl. 2019 Dec;21(Suppl L):L12-L16. doi: 10.1093/eurheartj/suz238. Epub 2019 Dec 23.
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Fifteen years of progress in understanding frailty and health in aging.十五年来对衰老过程中脆弱性和健康的认识进展。
BMC Med. 2018 Nov 27;16(1):220. doi: 10.1186/s12916-018-1223-3.
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Frailty in Heart Failure: Implications for Management.心力衰竭中的衰弱:对管理的影响。
Card Fail Rev. 2018 Aug;4(2):104-106. doi: 10.15420/cfr.2018.22.2.