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由药剂师主导的针对哮喘患者的干预措施的一致性和可重复性:意大利药物使用评估(I-MUR)。

Consistency and replicability of a pharmacist-led intervention for asthma patients: Italian Medicines Use Review (I-MUR).

作者信息

Manfrin Andrea, Krska Janet

机构信息

1Senior Lecturer in Pharmacy Practice,Sussex Pharmacy,School of Life Sciences,University of Sussex,Falmer,Brighton,UK.

2Professor of Clinical and Professional Practice,Medway School of Pharmacy,Universities of Greenwich and Kent at Medway,Anson Building,Central Avenue,Chatham Maritime,Chatham,Kent,UK.

出版信息

Prim Health Care Res Dev. 2019 Jan;20:e10. doi: 10.1017/S1463423618000580. Epub 2018 Sep 13.

Abstract

UNLABELLED

AimThis study aimed to assess the consistency and replicability of these process measures during provision of the Italian Medicines Use Review (I-MUR).

BACKGROUND

Medication review is a common intervention provided by community pharmacists in many countries, but with little evidence of consistency and replicability. The I-MUR utilised a standardised question template in two separate large-scale studies. The template facilitated pharmacists in recording medicines and problems reported by patients, the pharmaceutical care issues (PCIs) they found and actions they took to improve medicines use.

METHODS

Community pharmacists from four cities and across 15 regions were involved in the two studies. Patients included were adults with asthma. Medicines use, adherence, asthma problems, PCIs and actions taken by pharmacists were compared across studies to assess consistency and replicability of I-MUR.FindingsThe total number of pharmacists and patients completing the studies was 275 and 1711, respectively. No statistically significant differences were found between the studies in the following domains: patients' demographic, patients' perceived problems, adherence, asthma medicines used and healthy living advice provided by pharmacists. The proportion of patients in which pharmacists identified PCIs was similar across both studies. There were differences only in the incidence of non-steroidal anti-inflammatory drug use, the frequency of potential drug-disease interactions and in the types of advice given to patients and GPs.

CONCLUSIONS

The use of a standardised template for the I-MUR may have contributed to a degree of consistency in the issues found, which suggests this intervention could have good replicability.

摘要

未标注

目的

本研究旨在评估在提供意大利药物使用评估(I-MUR)过程中这些过程指标的一致性和可重复性。

背景

药物评估是许多国家社区药剂师提供的常见干预措施,但几乎没有一致性和可重复性的证据。I-MUR在两项独立的大规模研究中使用了标准化问题模板。该模板有助于药剂师记录患者报告的药物和问题、他们发现的药学服务问题(PCI)以及他们为改善药物使用所采取的行动。

方法

来自四个城市和15个地区的社区药剂师参与了这两项研究。纳入的患者为成年哮喘患者。对两项研究中的药物使用、依从性、哮喘问题、PCI以及药剂师采取的行动进行比较,以评估I-MUR的一致性和可重复性。

结果

完成研究的药剂师和患者总数分别为275人和1711人。在以下方面,两项研究之间未发现统计学上的显著差异:患者的人口统计学特征、患者感知到的问题、依从性、使用的哮喘药物以及药剂师提供的健康生活建议。两项研究中,药剂师识别出PCI的患者比例相似。仅在非甾体抗炎药的使用发生率、潜在药物-疾病相互作用的频率以及给予患者和全科医生的建议类型方面存在差异。

结论

I-MUR使用标准化模板可能在一定程度上促成了所发现问题的一致性,这表明该干预措施可能具有良好的可重复性。

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