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Are Cyst-Associated Macrophages in Polycystic Kidney Disease the Equivalent to TAMs in Cancer?多囊肾病中与囊肿相关的巨噬细胞等同于癌症中的肿瘤相关巨噬细胞吗?
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Immune checkpoint activity regulates polycystic kidney disease progression.免疫检查点活性调节多囊肾病的进展。
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Shared pathobiology identifies AMPK as a therapeutic target for obesity and autosomal dominant polycystic kidney disease.共同的病理生物学表明,AMPK是肥胖症和常染色体显性多囊肾病的治疗靶点。
Front Mol Biosci. 2022 Aug 23;9:962933. doi: 10.3389/fmolb.2022.962933. eCollection 2022.
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Quest for the Cure: Testing the Old and New to Prevent Progression of Autosomal Dominant Polycystic Kidney Disease.寻求治愈方法:新旧方法测试以预防常染色体显性多囊肾病的进展
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STAT signaling in polycystic kidney disease.STAT 信号通路在多囊肾病中的作用。
Cell Signal. 2020 Aug;72:109639. doi: 10.1016/j.cellsig.2020.109639. Epub 2020 Apr 20.
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Crystal deposition triggers tubule dilation that accelerates cystogenesis in polycystic kidney disease.晶体沉积引发小管扩张,加速多囊肾病的囊肿发生。
J Clin Invest. 2019 Jul 30;129(10):4506-4522. doi: 10.1172/JCI128503.

本文引用的文献

1
Mcp1 Promotes Macrophage-Dependent Cyst Expansion in Autosomal Dominant Polycystic Kidney Disease.Mcp1 促进常染色体显性多囊肾病中巨噬细胞依赖性囊肿扩张。
J Am Soc Nephrol. 2018 Oct;29(10):2471-2481. doi: 10.1681/ASN.2018050518. Epub 2018 Sep 12.
2
Inflammation and Fibrosis in Polycystic Kidney Disease.多囊肾病中的炎症与纤维化
Results Probl Cell Differ. 2017;60:323-344. doi: 10.1007/978-3-319-51436-9_12.
3
Tumor-associated macrophages: unwitting accomplices in breast cancer malignancy.肿瘤相关巨噬细胞:乳腺癌恶性发展中的不知情同谋。
NPJ Breast Cancer. 2016;2:15025-. doi: 10.1038/npjbcancer.2015.25. Epub 2016 Jan 20.
4
Macrophage migration inhibitory factor promotes cyst growth in polycystic kidney disease.巨噬细胞移动抑制因子促进多囊肾病中的囊肿生长。
J Clin Invest. 2015 Jun;125(6):2399-412. doi: 10.1172/JCI80467. Epub 2015 May 11.
5
Macrophages promote polycystic kidney disease progression.巨噬细胞促进多囊肾病的进展。
Kidney Int. 2013 May;83(5):855-64. doi: 10.1038/ki.2012.446. Epub 2013 Feb 20.
6
Signal transducer and activator of transcription-6 (STAT6) inhibition suppresses renal cyst growth in polycystic kidney disease.信号转导子和转录激活子-6(STAT6)抑制可抑制多囊肾病中的肾囊肿生长。
Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18067-72. doi: 10.1073/pnas.1111966108. Epub 2011 Oct 24.
7
Macrophages promote cyst growth in polycystic kidney disease.巨噬细胞促进多囊肾病囊肿生长。
J Am Soc Nephrol. 2011 Oct;22(10):1809-14. doi: 10.1681/ASN.2011010084. Epub 2011 Sep 15.
8
Third-hit signaling in renal cyst formation.肾囊肿形成中的第三次打击信号传导。
J Am Soc Nephrol. 2011 May;22(5):793-5. doi: 10.1681/ASN.2011030284. Epub 2011 Apr 14.
9
Distinct macrophage phenotypes contribute to kidney injury and repair.不同的巨噬细胞表型有助于肾脏损伤和修复。
J Am Soc Nephrol. 2011 Feb;22(2):317-26. doi: 10.1681/ASN.2009060615.
10
Polycystic kidney disease and renal injury repair: common pathways, fluid flow, and the function of polycystin-1.多囊肾病与肾损伤修复:共同途径、流体流动及多囊蛋白-1的功能
Am J Physiol Renal Physiol. 2007 Nov;293(5):F1423-32. doi: 10.1152/ajprenal.00275.2007. Epub 2007 Aug 22.

Are Cyst-Associated Macrophages in Polycystic Kidney Disease the Equivalent to TAMs in Cancer?

作者信息

Weimbs Thomas

机构信息

Department of Molecular, Cellular, and Developmental Biology and Neuroscience Research Institute, University of California, Santa Barbara, California

出版信息

J Am Soc Nephrol. 2018 Oct;29(10):2447-2448. doi: 10.1681/ASN.2018080846. Epub 2018 Sep 12.

DOI:10.1681/ASN.2018080846
PMID:30209077
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6171269/
Abstract
摘要