Beeskow Anne B, Oberstadt Moritz, Saur Dorothee, Hoffmann Karl-Titus, Lobsien Donald
Department of Pediatric Radiology, University Hospital Leipzig, Leipzig, Germany.
Department of Neurology, University Hospital Leipzig, Leipzig, Germany.
Front Neurol. 2018 Aug 27;9:708. doi: 10.3389/fneur.2018.00708. eCollection 2018.
Delayed post-hypoxic leukoencephalopathy (DPHL) is an uncommon, potentially under-recognized, cause of hypoxia induced white matter injury. It characteristically follows a biphasic course: After an initial phase of altered neurologic status a recovery occurs which is then followed by a recurring phase of neurologic deterioration, typically 2-4 weeks after the initial event. At this time white matter changes can be identified on MRI, which are the hallmark of DPHL. The characteristics and the typical MR-imaging signs of DPHL are discussed in this case report.
迟发性缺氧后白质脑病（DPHL）是一种罕见的、可能未被充分认识的缺氧性白质损伤原因。其典型病程呈双相性：在最初的神经功能状态改变阶段之后会出现恢复，随后是神经功能恶化的复发阶段，通常在初始事件发生后2 - 4周出现。此时，磁共振成像（MRI）上可发现白质改变，这是DPHL的标志。本病例报告讨论了DPHL的特征及典型的磁共振成像征象。
