Marotta M, D'Armiento F P, Martino G, Donato G, Nazzaro A, Vecchione R, Rosati P
Appl Pathol. 1985;3(3):164-9.
The authors evaluate the distribution and the content of glycosaminoglycans (GAG) in neoplastic tissue from mastectomy specimens of 15 patients treated for an infiltrating ductal carcinoma NOS, in comparison to normal tissue of the opposite quadrant. Neoplastic tissues contain a marked amount (5 mg/g dry defatted tissue) of GAG, in comparison to normal ones (2.2 mg/g dry defatted weight). In stellate carcinomas GAG are localized near the interface with the host tissue and are constituted mainly of chondroitin sulfates and hyaluronate. These data are confirmed by electrophoretic analysis.
作者评估了15例浸润性导管癌NOS患者乳房切除标本的肿瘤组织中糖胺聚糖（GAG）的分布和含量，并与对侧象限的正常组织进行了比较。与正常组织（2.2mg/g干脱脂重量）相比，肿瘤组织含有大量（5mg/g干脱脂组织）的GAG。在星状癌中，GAG定位于与宿主组织的界面附近，主要由硫酸软骨素和透明质酸组成。这些数据通过电泳分析得到证实。
