人类乳腺癌中的胶原蛋白：形态学与生物化学研究
Collagen in human breast cancer: morphological and biochemical study.
作者信息
Marotta M, Martino G, D'Armiento F P, Aiello A M, Roberti M L, Vecchione R, Rosati P
出版信息
Appl Pathol. 1985;3(3):170-8.
PMID:3021187
Abstract
The authors studied the distribution and the composition of collagen in neoplastic tissue from mastectomy specimens of 15 patients treated for an infiltrating ductal carcinoma NOS, in comparison to normal tissue of the opposite quadrant. The study was performed by light microscopy, microspectrophotometry, and electrophoretic methods. The results demonstrate a characteristic stromal organization of breast cancer in relation to collagen type I content.
摘要
作者研究了15例浸润性导管癌（非特殊类型）患者乳房切除标本中肿瘤组织内胶原蛋白的分布和组成，并与对侧象限的正常组织进行比较。该研究通过光学显微镜、显微分光光度法和电泳方法进行。结果表明，乳腺癌的基质组织在I型胶原蛋白含量方面具有特征性。
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