Minafra S, Minafra I P, Tomasino R M, Sciarrino S
Cell Biol Int Rep. 1984 Jan;8(1):79-85. doi: 10.1016/0309-1651(84)90184-x.
Ductal infiltrating carcinoma of the breast is characterized by a remarkable amount of collagen fibrils surrounding nests and cords of neoplastic cells. Sequential extractions with pepsin release three classes of intact collagen chains, which have been identified as alpha 1 (I), alpha 2 (I) and alpha 1 (III) types. Alpha 1 (I) is prominent among these classes.
乳腺导管浸润癌的特征是肿瘤细胞巢和索周围有大量胶原纤维。用胃蛋白酶连续提取可释放出三类完整的胶原链，已鉴定为α1（I）、α2（I）和α1（III）型。其中α1（I）最为突出。
