Badran Karam W, Sand Jordan P
Department of Head and Neck Surgery, David Geffen School of Medicine, University of California, Los Angeles, 10833 Le Conte Avenue, CHS 62-237, Los Angeles, CA 90095, USA.
Spokane Center for Facial Plastic Surgery, 217 West Cataldo Avenue, Spokane, WA 99201, USA; Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, 1959 NE Pacific Street, Seattle, WA 98195, USA.
Facial Plast Surg Clin North Am. 2018 Nov;26(4):469-485. doi: 10.1016/j.fsc.2018.06.008. Epub 2018 Aug 16.
Given substantial advances in hair regrowth research and platelet-rich plasma (PRP) science, a review of currently used systems and results is informative for physicians using a biologics approach to hair restoration. Overall positive clinical response to the use of PRP in androgenetic and alopecia areata patients is observed. The effects on hair density, count, and thickness were demonstrated through multiple clinical trials. Use as an adjunct to hair transplantation and with other technologies is also described. When compared with traditional oral/topical treatments, the lack of identifiable complications and convenience of treatment provide a positive outlook for future use and investigation.
鉴于毛发再生研究和富血小板血浆（PRP）科学取得了重大进展，对目前使用的系统和结果进行综述，对于采用生物制剂方法进行毛发修复的医生来说是很有参考价值的。总体而言，观察到在雄激素性脱发和斑秃患者中使用PRP有积极的临床反应。多项临床试验证明了其对头发密度、数量和厚度的影响。还介绍了其作为植发辅助手段以及与其他技术联合使用的情况。与传统的口服/局部治疗相比，其缺乏可识别的并发症以及治疗的便利性为未来的使用和研究提供了积极的前景。
