Fousekis Fotios S, Theopistos Vasileios I, Katsanos Konstantinos H, Christodoulou Dimitrios K
Department of Gastroenterology and Hepatology, Medical School of Ioannina, Greece.
J Clin Med Res. 2018 Oct;10(10):743-751. doi: 10.14740/jocmr3561w. Epub 2018 Sep 10.
Inflammatory bowel disease (IBD) is a multisystemic disease, and pancreatic manifestations of IBD are not uncommon. The incidence of several pancreatic diseases in Crohn's disease and ulcerative colitis is more frequent compared to the general population. Pancreatic manifestations in IBD include a wide heterogenic group of disorders and abnormalities of the pancreas and range from mild self-limited diseases to severe disorders. Acute pancreatitis, chronic pancreatitis, autoimmune pancreatitis, pancreatic autoantibodies, exocrine pancreatic insufficiency and asymptomatic imaging and laboratory abnormalities are included in related-IBD pancreatic manifestations. Involvement of the pancreas in IBD may be the result of IBD itself or of medications used.
炎症性肠病(IBD)是一种多系统疾病,IBD的胰腺表现并不罕见。与普通人群相比,克罗恩病和溃疡性结肠炎中几种胰腺疾病的发病率更高。IBD的胰腺表现包括一大组异质性的胰腺疾病和异常情况,范围从轻度自限性疾病到严重疾病。急性胰腺炎、慢性胰腺炎、自身免疫性胰腺炎、胰腺自身抗体、外分泌性胰腺功能不全以及无症状的影像学和实验室异常均包括在与IBD相关的胰腺表现中。胰腺受累于IBD可能是IBD本身或所用药物导致的结果。