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儿童期起病的炎症性肠病与成年期精神疾病共病之间的关联。

Association between Childhood Onset Inflammatory Bowel Disease and Psychiatric Comorbidities in Adulthood.

作者信息

Sălcudean Andreea, Nan Andreea Georgiana, Bodo Cristina Raluca, Cosma Marius Cătălin, Strete Elena Gabriela, Lica Maria Melania

机构信息

Department M2, Discipline of Bioethics, Social & Human Sciences, University of Medicine and Pharmacy, Sciences and Technology George Emil Palade of Targu Mures, 540142 Targu Mures, Romania.

First Department of Psychiatry, Clinical County Hospital of Targu Mures, 540142 Targu Mures, Romania.

出版信息

Diagnostics (Basel). 2023 May 26;13(11):1868. doi: 10.3390/diagnostics13111868.

Abstract

Inflammatory bowel disease (IBD), which includes Crohn's disease, ulcerative colitis, and unspecified inflammatory bowel disease, is a chronic, unpredictable and immune-mediated condition of the gastrointestinal tract. In pediatric populations, the diagnosis of a chronic and debilitating pathology significantly reduces quality of life. Children diagnosed with IBD may cope with physical symptoms such as abdominal pain or fatigue, but mental and emotional well-being are also important for preventing and reducing the risk of developing psychiatric conditions. Short stature, growth delay and delayed puberty can contribute to poor body image and low self-esteem. Furthermore, treatment per se can alter psycho-social functioning due to the side effects of medication and surgical procedures such as colostomy. It is essential to acknowledge and treat early signs and symptoms of psychiatric distress in order to prevent the development of serious psychiatric disorders in adult life. The literature underlines the importance of incorporating psychological and mental health services as part of the management of inflammatory bowel disease. Diagnosing mental health problems in pediatric patients with IBD can improve their adherence to treatment and pathology course and, consequently, reduce long-term morbidity and mortality.

摘要

炎症性肠病(IBD)包括克罗恩病、溃疡性结肠炎和未特定的炎症性肠病,是一种慢性、不可预测且由免疫介导的胃肠道疾病。在儿科人群中,慢性衰弱性疾病的诊断会显著降低生活质量。被诊断为IBD的儿童可能要应对腹痛或疲劳等身体症状,但心理和情绪健康对于预防和降低患精神疾病的风险也很重要。身材矮小、生长发育迟缓以及青春期延迟会导致身体形象不佳和自尊心低落。此外,由于药物副作用和诸如结肠造口术等外科手术,治疗本身会改变心理社会功能。认识并治疗精神困扰的早期迹象和症状,对于预防成年后严重精神障碍的发生至关重要。文献强调了将心理和心理健康服务纳入炎症性肠病管理的重要性。诊断患有IBD的儿科患者的心理健康问题可以提高他们对治疗和病程的依从性,从而降低长期发病率和死亡率。

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