Wong Mimi, Inder Warrick J
Department of Diabetes and Endocrinology Princess Alexandra Hospital Brisbane QLD Australia.
Faculty of Medicine The University of Queensland Brisbane QLD Australia.
Clin Case Rep. 2018 Jul 9;6(9):1684-1688. doi: 10.1002/ccr3.1700. eCollection 2018 Sep.
Spontaneously oscillating thyroid function in Graves' disease is a rare phenomenon. Switching between TSH receptor stimulating antibodies (TSAb) and TSH receptor blocking antibodies (TBAb) most likely accounts for presentations of alternating hyperthyroidism and hypothyroidism. To achieve stability of thyroid function, definitive therapy is recommended to remove the pathological thyroid.
格雷夫斯病中甲状腺功能的自发振荡是一种罕见现象。促甲状腺激素受体刺激抗体(TSAb)和促甲状腺激素受体阻断抗体(TBAb)之间的转换很可能是甲亢和甲减交替出现的原因。为实现甲状腺功能的稳定,建议采取确定性治疗以切除病理性甲状腺。