慢性淋巴细胞白血病中的自发淋巴细胞转化
Spontaneous lymphocyte transformation in chronic lymphocytic leukaemia.
作者信息
Semenzato G, Amadori G, Tosato F, Gasparotto G
出版信息
Clin Exp Immunol. 1977 Jun;28(3):542-5.
Abstract
In ten patients with CLL and in eight controls T lymphocytes were separated out by the rosetting method. The in vitro reactivity of these cells and of unseparated lymphocytes was studied in cultures without stimulants. A net increase of spontaneous lymphocyte transformation was found in the populations enriched with T cells in patients with CLL with respect to analogous populations in the controls. This increase is interpreted as a cell-mediated immunological reaction and due to T-cell sensitization towards the neoplastic B cells.
摘要
采用玫瑰花结法从10例慢性淋巴细胞白血病患者和8例对照者中分离出T淋巴细胞。在无刺激物的培养物中研究了这些细胞和未分离淋巴细胞的体外反应性。与对照组的类似群体相比，慢性淋巴细胞白血病患者中富含T细胞的群体中自发淋巴细胞转化出现净增加。这种增加被解释为一种细胞介导的免疫反应，是由于T细胞对肿瘤性B细胞的致敏作用。
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本文引用的文献
1
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3
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Cell Immunol. 1973 Jan;6(1):140-8. doi: 10.1016/0008-8749(73)90014-2.
4
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Blood. 1972 Dec;40(6):777-94.
5
Immunoglobulins on the surface of neoplastic lymphocytes.肿瘤淋巴细胞表面的免疫球蛋白。
N Engl J Med. 1972 Aug 10;287(6):272-6. doi: 10.1056/NEJM197208102870603.
6
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Scand J Haematol. 1974;13(5):352-60. doi: 10.1111/j.1600-0609.1974.tb00281.x.
7
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Ann Rheum Dis. 1974 Jul;33(4):361-5. doi: 10.1136/ard.33.4.361.
8
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9
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