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[123I]碘安非他明单光子发射计算机断层显像

[123I]iodoamphetamine SPECT imaging.

作者信息

Cohen M B, Graham L S, Yamada L S

出版信息

Int J Rad Appl Instrum A. 1986;37(8):749-63. doi: 10.1016/0883-2889(86)90270-4.

Abstract

SPECT imaging of [123I]IMP is reviewed. Methods for radiopharmaceutical production are discussed with an emphasis on labeling small quantities of IMP. Limited angle tomography and full angle SPECT with standard cameras and special imaging systems are reviewed. Selection of collimator and methods of reconstruction are discussed. Clinical studies are described with emphasis on stroke, epilepsy and dementia. The efforts to perform quantitative imaging of rCBF with [123I]IMP are reviewed.

摘要

本文综述了[123I]IMP的单光子发射计算机断层扫描(SPECT)成像。讨论了放射性药物的生产方法,重点是少量IMP的标记。综述了使用标准相机和特殊成像系统的有限角度断层扫描和全角度SPECT。讨论了准直器的选择和重建方法。描述了临床研究,重点是中风、癫痫和痴呆。综述了使用[123I]IMP进行脑血流量(rCBF)定量成像的研究工作。

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