新生儿基孔肯雅热的脑炎表现：病例系列
Encephalitic presentation of Neonatal Chikungunya: A Case Series.
作者信息
Maria Arti, Vallamkonda Nagaratana, Shukla Amlin, Bhatt Aditya, Sachdev Namrita
机构信息
Department of Neonatology, Postgraduate Institute of Medical Education and Research and Dr RML Hospital, New Delhi, India. Correspondence to: Dr Arti Maria, Professor and Head, Department of Neonatology, PGIMER and Dr RML Hospital, New Delhi 110 001, India.
Department of Neonatology, Postgraduate Institute of Medical Education and Research and Dr RML Hospital, New Delhi, India.
出版信息
Indian Pediatr. 2018 Aug 15;55(8):671-674.
OBJECTIVE
To describe clinical features and early neurological outcomes in neonatal Chikungunya.
METHODS
Clinical, pathological and radiological details of neonates with acute encephalitic features and typical rash, later diagnosed as Chikungunya, are presented. Neurodevelopmental evaluation and imaging was done at discharge/three months.
RESULTS
Abnormal neurological examination with fever was typical presentation in all 13 babies with/without seizures/peri-oral rashes; 12 had persistent neurological abnormalities at discharge. A follow-up at three months revealed continued neurodevelopmental deficits. Neuroimaging abnormalities were seen in eight out of ten cases.
CONCLUSIONS
Perinatal Chikungunya should be considered in neonates presenting within first week with fever, encephalopathy and perioral rashes with/without seizures with history of maternal Chikungunya within last week before delivery.
目的
描述新生儿基孔肯雅热的临床特征及早期神经学转归。
方法
介绍了具有急性脑炎特征和典型皮疹、后来被诊断为基孔肯雅热的新生儿的临床、病理和放射学细节。在出院时/三个月时进行神经发育评估和影像学检查。
结果
13例有/无惊厥/口周皮疹的婴儿的典型表现为发热时神经检查异常；12例在出院时有持续性神经异常。三个月的随访显示神经发育缺陷持续存在。10例中有8例出现神经影像学异常。
结论
对于在出生后第一周内出现发热、脑病和口周皮疹、有/无惊厥且母亲在分娩前最后一周有基孔肯雅热病史的新生儿，应考虑围产期基孔肯雅热。
Zotero 插件