1型呼肠孤病毒分泌到胆汁中。
Reovirus type 1 is secreted into the bile.
作者信息
Rubin D H, Eaton M A, Costello T
出版信息
J Virol. 1986 Nov;60(2):726-8. doi: 10.1128/JVI.60.2.726-728.1986.
Abstract
Reovirus type 1, known to be a cause of systemic and intestinal disease in mice, is secreted into the bile of adult A/J mice after viremia. Virus found in the bile in concentrations higher than those in blood may indicate that reovirus type 1 is actively transported into the bile. The transport of virus was independent of levels of virus-specific immunoglobulin A antibody. Modifications of the virus that occurred during transport did not discernibly affect the infectivity of the virus. Entry of virus into the bile may be an important mechanism by which an enteric virus that produces systemic disease reenters the intestine for transmission.
摘要
1型呼肠孤病毒是已知的可引起小鼠全身性和肠道疾病的病原体，在病毒血症后会分泌到成年A/J小鼠的胆汁中。胆汁中发现的病毒浓度高于血液中的浓度，这可能表明1型呼肠孤病毒被主动转运到胆汁中。病毒的转运与病毒特异性免疫球蛋白A抗体的水平无关。转运过程中发生的病毒修饰对病毒的感染性没有明显影响。病毒进入胆汁可能是一种重要机制，通过该机制，产生全身性疾病的肠道病毒可重新进入肠道进行传播。
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本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
The response of mice to large intravenous injections of ectromelia virus. I. The fate of injected virus.小鼠对大剂量静脉注射埃可病毒的反应。I. 注射病毒的归宿
Br J Exp Pathol. 1959 Dec;40(6):533-42.
3
Rift Valley fever virus in mice. VI. Histological changes in the liver in relation to virus multiplication.
Aust J Exp Biol Med Sci. 1957 Dec;35(6):595-604. doi: 10.1038/icb.1957.61.
4
The elimination of circulating complexes containing polymeric IgA by excretion in the bile.通过胆汁排泄清除含有聚合型IgA的循环复合物。
Immunology. 1981 Jan;42(1):83-9.
5
Evidence for a vesicular transport mechanism in hepatocytes for biliary secretion of immunoglobulin A.肝细胞中存在免疫球蛋白A胆汁分泌的囊泡转运机制的证据。
Science. 1980 Jun 13;208(4449):1276-8. doi: 10.1126/science.7375938.
6
Elimination of intestinally absorbed antigen into the bile by IgA.
J Immunol. 1984 Feb;132(2):780-2.
7
Determinants of reovirus interaction with the intestinal M cells and absorptive cells of murine intestine.呼肠孤病毒与小鼠肠道M细胞及吸收细胞相互作用的决定因素。
Gastroenterology. 1983 Aug;85(2):291-300.
8
Cellular mechanisms of bile formation.胆汁形成的细胞机制。
Gastroenterology. 1982 Feb;82(2):346-57.
9
Intestinal M cells: a pathway for entry of reovirus into the host.肠道M细胞：呼肠孤病毒进入宿主的一条途径。
Science. 1981 Apr 24;212(4493):471-2. doi: 10.1126/science.6259737.
10
Bile formation: sites and mechanisms.胆汁形成：部位与机制
Hepatology. 1984 Sep-Oct;4(5 Suppl):15S-24S. doi: 10.1002/hep.1840040804.
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