[Comparison of swept source anterior segment optical coherence tomography and ultrasound biomicroscopy in measurement of anterior chamber depth and anterior chamber angle data in age-related cataract patients].

To explore the difference and agreement in the measurement of anterior chamber depth (ACD) and anterior chamber angle data in age-related cataract patients between swept source anterior segment optical coherence tomography (SS-AS-OCT) and ultrasound biomicroscopy (UBM). A prospective study. Forty-five eyes from 45 age-related cataract patients were selected at Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University from November to December 2016. There were 23 males and 22 females aged (51±19) years. SS-AS-OCT and UBM were used to measure the ACD, angle opening distance (AOD 500) and trabecular-iris angle (TIA 500). The paired samples -test and Pearson linear correlation were used for statistical analysis, and the Bland-Altman analysis was used to evaluate the measurement consistency of the two tools. The ACD measured by SS-AS-OCT and UBM was (2.750±0.544) mm and (2.775±0.531) mm, respectively, the difference was statistically significant (2.109, 0.040), and the measurement results were positively correlated (0.989, 0.001). In the nasal, temporal, upper and lower positions, the AOD 500 and TIA 500 values measured by SS-AS-OCT and UBM had a significant difference [AOD 500: (0.451±0.201) mm .(0.421±0.194) mm, (0.499±0.229) mm . (0.465±0.207) mm, (0.390±0.215) mm . (0.355±0.208) mm, (0.441±0.226) mm . (0.423±0.215) mm, 4.262, 4.350, 5.355, 4.415; TIA 500: 39.587°±14.698°. 36.944°±13.790°, 42.149°±14.138°. 40.289°±13.041°, 36.482°±15.887°. 35.600°±15.215°, 38.504°±14.805°. 36.818°±14.931°, 5.131, 4.658, 4.174, 5.731; all 0.001] and a significant linear correlation (AOD 500: 0.971, 0.975, 0.979, 0.973; TIA 500: 0.972, 0.957, 0.956, 0.970; all 0.001). The Bland-Altman method showed that the two modalities had comparable results for the ACD, AOD 500 and TIA 500 (2.22%-6.67% of the measured value outside the 95% consistency boundaries). SS-OCT and UBM show a good agreement in the measurement of ACD and anterior chamber angle data in age-related cataract patients, though there is difference between them in measurement results. .