Zhong Lu, Zuo Jing, Jin Qingzi, Xing Jing, Zhou Xin
Department of Ophthalmology, Jiangsu Province Hospital of Chinese Medicine Nanjing 210029, Jiangsu Province, China.
Am J Transl Res. 2021 Apr 15;13(4):3156-3164. eCollection 2021.
To explore the changes of anatomical biological parameters and dynamic parameters of the anterior segment (AS) before and after primary angle closure glaucoma (PACG) surgery.
The clinical data of 82 patients (82 eyes) who underwent phacoemulsification in our hospital were retrospectively analyzed and divided into group A (angle closure, n = 38) and group B (normal open angle, n = 44). The anatomical biological parameters and dynamic parameters were compared between the two groups before and after surgery.
Compared with group B, group A had smaller anterior chamber depth, higher vaulting, greater iris curvature, and smaller TISA500. Compared with group B, group A had smaller ΔTISA500 and ΔI-area. Compared with group B, the TISA500 was smaller in group A preoperatively, at 1 week, and 1 month after surgery ( < 0.05). The iris curvature was larger in group A ( < 0.05). The ΔI-area was significantly reduced in group B at 1 week and 1 month after surgery. Group B exhibited smaller ΔI-curv than group A at 1 week and 1 month after surgery ( < 0.05).
Anterior segment optical coherence tomography (AS-OCT) can effectively monitor the dynamic changes (DC) of the AS caused by phacoemulsification in patients with primary angle closure (PAC). Phacoemulsification can open the primary of PAC patients. However, their iris area does not change significantly. The biological characteristics of the iris itself may be a risk factor leading to PAC.
探讨原发性闭角型青光眼(PACG)手术前后眼前段(AS)解剖学和动态参数的变化。
回顾性分析我院82例行超声乳化手术患者(82只眼)的临床资料,分为A组(闭角型,n = 38)和B组(正常开角型,n = 44)。比较两组手术前后的解剖学和动态参数。
与B组相比,A组前房深度较小,房角穹窿较高,虹膜曲率较大,TISA500较小。与B组相比,A组的ΔTISA500和ΔI区较小。与B组相比,A组术前、术后1周和1个月时的TISA500较小(<0.05)。A组的虹膜曲率较大(<0.05)。B组术后1周和1个月时的ΔI区明显减小。B组术后1周和1个月时的ΔI曲率比A组小(<0.05)。
眼前段光学相干断层扫描(AS-OCT)可有效监测原发性闭角型(PAC)患者超声乳化术后眼前段的动态变化(DC)。超声乳化可打开PAC患者的房角。然而,其虹膜面积变化不明显。虹膜本身的生物学特性可能是导致PAC的危险因素。