临床红外显微成像：综述。
Clinical infrared microscopic imaging: An overview.
作者信息
Pallua J D, Brunner A, Zelger B, Stalder R, Unterberger S H, Schirmer M, Tappert M C
机构信息
Department of Pathology, Medical University of Innsbruck, Müllerstraße 44, 6020, Innsbruck, Austria; Institute of Legal Medicine, Medical University of Innsbruck, Müllerstraße 44, 6020, Innsbruck, Austria.
Department of Pathology, Medical University of Innsbruck, Müllerstraße 44, 6020, Innsbruck, Austria.
出版信息
Pathol Res Pract. 2018 Oct;214(10):1532-1538. doi: 10.1016/j.prp.2018.08.026. Epub 2018 Sep 4.
New developments in Mid-infrared microscopic imaging instrumentation and data analysis have turned this method into a conventional technique. This imaging method offers a global analysis of samples, with a resolution close to the cellular level enabling the acquisition of local molecular expression profiles. It is possible to get chemo-morphological information about the tissue status, which represents an essential benefit for future analytical interpretation of pathological changes of tissue. In this review, we give an overview of Mid-infrared microscopic imaging and its applications in clinical research.
中红外显微成像仪器和数据分析的新进展已将该方法转变为一种常规技术。这种成像方法可对样品进行全局分析，分辨率接近细胞水平，能够获取局部分子表达谱。有可能获得有关组织状态的化学形态学信息，这对未来组织病理变化的分析解释具有重要意义。在本综述中，我们概述了中红外显微成像及其在临床研究中的应用。
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