Sullivan Helen W, O'Donoghue Amie C, Aikin Kathryn J
1 US Food and Drug Administration, Silver Spring, MD, USA.
Ther Innov Regul Sci. 2015 Jul;49(4):493-502. doi: 10.1177/2168479015572370.
Previous research demonstrated that providing qualitative and quantitative information in a "drug facts box" may help individuals understand prescription drug information in print-based direct-to-consumer advertisements. The authors sought to determine whether qualitative, quantitative, or a combination thereof best communicates benefit and risk information.
To replicate and extend previous research, the authors used simple quantitative drug information. A randomized controlled study was conducted with 5067 Internet panelists with heartburn. Participants viewed a drug facts box with benefit and risk information that varied the presence or absence of qualitative summaries and absolute frequencies, percentages, and absolute differences. Measures included knowledge of drug benefits and risks, perceptions, and intentions.
Providing absolute frequencies and percentages most improved participants' drug knowledge and affected perceptions and intentions.
The study findings suggest that, for simple drug information, adding absolute frequencies and percentages to direct-to-consumer advertisements may benefit consumers. Absolute differences and qualitative labels may not be needed.
先前的研究表明，在“药品说明书”中提供定性和定量信息可能有助于个人理解基于印刷品的面向消费者的直接广告中的处方药信息。作者试图确定定性、定量或两者结合是否能最好地传达益处和风险信息。
为了重复和扩展先前的研究，作者使用了简单的定量药物信息。对5067名有胃灼热问题的互联网小组成员进行了一项随机对照研究。参与者查看了一个包含益处和风险信息的药品说明书，其中定性总结以及绝对频率、百分比和绝对差异的有无各不相同。测量指标包括对药物益处和风险的了解、认知和意图。
提供绝对频率和百分比最能提高参与者的药物知识，并影响认知和意图。
研究结果表明，对于简单的药物信息，在面向消费者的广告中添加绝对频率和百分比可能会使消费者受益。可能不需要绝对差异和定性标签。
