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[银化合物对水中病毒的影响]

[Effect of silver compounds on viruses in water].

作者信息

Mahnel H, Schmidt M

出版信息

Zentralbl Bakteriol Mikrobiol Hyg B Umwelthyg Krankenhaushyg Arbeitshyg Prav Med. 1986 Jul;182(4):381-92.

PMID:3022501
Abstract

Two commercial substances, Certisil and Micropur, containing microbicidal silver compounds and destinated for decontamination as well as preservation of water were examined for virus inactivating activity against ECBO-, influenza A, Newcastle Disease, pseudorabies and vaccinia viruses in drinking water. In the recommended concentration as well as higher concentrated the lability of the viruses was increased by the silver compounds. This activity which cannot be designated as a true virucidal effect was clearly evident in the case of ECBO and vaccinia viruses, moderate on influenza and pseudorabies viruses but insignificant on Newcastle disease virus. Two combined silver compounds, Certisil-Combina and Sanosil, each containing an immediate microbicidal part besides silver differed in their antiviral activity. The chlorine separating part of Certisil-Combina didn't cause an improvement or acceleration of the destabilizing effect on viruses compared to the pure silver compound, while the hydrogen peroxide part of Sanosil led to a better and continuing inactivating influence on the viruses which were merely reduced in infectivity by 99,9% within one day. Only in the case of evident or suspected contamination of water reservoirs by viruses the addition of a combined silver drug with oxygen separating part seems to be useful.

摘要

对两种商业产品Certisil和Micropur进行了检测,它们含有杀菌银化合物,用于水的净化和保存,检测其对饮用水中埃可病毒B型(ECBO)、甲型流感病毒、新城疫病毒、伪狂犬病病毒和痘苗病毒的病毒灭活活性。在推荐浓度以及更高浓度下,银化合物会增加病毒的不稳定性。这种活性不能被称为真正的杀病毒作用,在ECBO病毒和痘苗病毒的情况下明显可见,对流感病毒和伪狂犬病病毒的作用中等,但对新城疫病毒则不显著。两种复合银化合物Certisil-Combina和Sanosil,除了银之外各自还含有一种即时杀菌成分,它们的抗病毒活性有所不同。与纯银化合物相比,Certisil-Combina的氯释放部分并没有使对病毒的去稳定作用得到改善或加速,而Sanosil的过氧化氢部分对病毒产生了更好且持续的灭活影响,这些病毒在一天内感染力仅降低了99.9%。只有在水源明显或疑似受到病毒污染的情况下,添加具有氧释放部分的复合银药物似乎才有用。

相似文献

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[Effect of silver compounds on viruses in water].[银化合物对水中病毒的影响]
Zentralbl Bakteriol Mikrobiol Hyg B Umwelthyg Krankenhaushyg Arbeitshyg Prav Med. 1986 Jul;182(4):381-92.

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