O'brien Lauren, Duong Jennifer, Winterton Tessa, Haring Anna, Kuhlmann Zachary
Obstetrician/Gynecologist at Avera Medical Group Marshall in Marshall, MN (lauren.o'
Research Associate in the Department of Obstetrics and Gynecology at the University of Kansas School of Medicine in Wichita (
Perm J. 2018;22:17-170. doi: 10.7812/TPP/17-170.
Preeclampsia with severe hypertension, which occurs in 5% to 8% of pregnancies, is a leading cause of maternal and perinatal morbidity and mortality in the US. Early recognition and treatment of hypertensive crises can significantly reduce poor outcomes. A protocol to ensure prompt treatment with antihypertensive medication (intravenous labetalol) was implemented at our institution.
To determine adherence to this protocol on the Labor and Delivery Unit.
Retrospective chart review was performed for patients admitted to the Labor and Delivery Unit between April 2015 and June 2015. Charts were reviewed if the patient had a diagnosis of chronic hypertension, gestational hypertension, superimposed preeclampsia, preeclampsia with severe features, eclampsia, or stroke in pregnancy. Only patients with confirmed severe blood pressures, in which the protocol would be initiated, were included in the final analysis.
Overall compliance with the entire protocol.
Of 178 cases reviewed, 58 (32.6%) had confirmed severe blood pressures. Most patients (n = 46, 79.3%) received a diagnosis of preeclampsia with severe features, and most delivered via cesarean delivery (n = 38, 65.5%). No cases were compliant with the entire labetalol protocol. Of 58 patients, 2 (3.5) adequately repeated a confirmation blood pressure within 5 minutes, and 34 (58.6%) were adequately treated with intravenous labetalol according to protocol requirements.
Labetalol treatment was appropriately initiated in many cases; however, protocol adherence could greatly improve. Potential factors affecting protocol compliance include shift changes, communication issues, and conflicting protocols. Institutions should review protocol compliance to improve care.
重度高血压子痫前期在美国5%至8%的妊娠中出现,是孕产妇和围产儿发病及死亡的主要原因。高血压危象的早期识别和治疗可显著降低不良结局。我们机构实施了一项确保及时使用抗高血压药物(静脉注射拉贝洛尔)治疗的方案。
确定分娩单元对该方案的依从性。
对2015年4月至2015年6月入住分娩单元的患者进行回顾性病历审查。如果患者诊断为慢性高血压、妊娠期高血压、子痫前期叠加症、重度子痫前期、子痫或妊娠合并中风,则审查病历。最终分析仅纳入确诊为重度血压且将启动该方案的患者。
对整个方案的总体依从性。
在审查的178例病例中,58例(32.6%)确诊为重度血压。大多数患者(n = 46,79.3%)被诊断为重度子痫前期,且大多数通过剖宫产分娩(n = 38,65.5%)。没有病例完全符合整个拉贝洛尔方案。在58例患者中,2例(3.5%)在5分钟内充分重复了确诊血压测量,34例(58.6%)根据方案要求接受了静脉注射拉贝洛尔的充分治疗。
在许多情况下,拉贝洛尔治疗已适当启动;然而,方案依从性仍可大幅提高。影响方案依从性的潜在因素包括班次交接、沟通问题和相互冲突的方案。各机构应审查方案依从性以改善护理。