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射频辐射对小鼠胎儿体重、体长和组织的影响。

The effects of radiofrequency radiation on mice fetus weight, length and tissues.

作者信息

Alimohammadi Iraj, Ashtarinezhad Azadeh, Asl Baharak Mohamadzadeh, Masruri Batol, Moghadasi Nargess

机构信息

Department of Occupational Health, School of public Health, Iran University of Medical Sciences, Tehran, Iran.

Department of Pharmacology and Toxicology, Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Data Brief. 2018 Jun 30;19:2189-2194. doi: 10.1016/j.dib.2018.06.107. eCollection 2018 Aug.

Abstract

The public concern of harmful effects of radiofrequency radiation exposure, especially with rapid increase in the use of wireless and telecommunication devices, is increasing. Some studies show fetal and developmental abnormalities as the result of radiofrequency radiation exposure. We aimed to investigate possible teratogenic effects of radiofrequency in 915 MHz on mice fetus and protective role of vitamin C. 21 pregnant mice were divided into 3 groups. Control group was in normal condition without any stressor agent. Exposure group was exposed to 915 MHz RFR (8 h/day for 10 days) and 0.045 µw/cm power density. The exposure plus vitamin C group received 200 mg/kg vitamin C by gavage and was exposed to 915 MHz RFR (8 h/day for 10 days) and 0.045 µw/cm power density. The fetus weight, C-R length were measured by digital balance and caliper. Tissues were assessed after staining with H & E. Our results showed significant increase in fetus weight and C-R length and also enlarged liver, tail deformation in mice fetus in exposure group. Although usage of vitamin C caused significant decrease in mentioned parameters. The outcome of this study confirms the effects of radiofrequency radiation on growth parameters such as body weight, length and some tissues in mice fetuses and protective effect of vitamin C. However more studies on non-ionization radiation in different frequencies and severity, during pregnancy are needed to clarify the exact mechanisms of these changes and better protection.

摘要

随着无线和电信设备使用的迅速增加,公众对射频辐射暴露有害影响的关注度日益提高。一些研究表明,射频辐射暴露会导致胎儿和发育异常。我们旨在研究915兆赫射频对小鼠胎儿的潜在致畸作用以及维生素C的保护作用。将21只怀孕小鼠分为3组。对照组处于正常状态,未接触任何应激源。暴露组暴露于915兆赫射频辐射(每天8小时,共10天),功率密度为0.045微瓦/平方厘米。暴露加维生素C组通过灌胃给予200毫克/千克维生素C,并暴露于915兆赫射频辐射(每天8小时,共10天),功率密度为0.045微瓦/平方厘米。用电子天平和平尺测量胎儿体重、头臀长度。用苏木精和伊红染色后评估组织。我们的结果显示,暴露组小鼠胎儿的体重和头臀长度显著增加,肝脏肿大,尾巴变形。尽管使用维生素C使上述参数显著降低。本研究结果证实了射频辐射对小鼠胎儿体重、长度等生长参数及某些组织的影响以及维生素C的保护作用。然而,需要对孕期不同频率和强度下的非电离辐射进行更多研究,以阐明这些变化的确切机制并提供更好的保护。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/994a/6141437/aaecca5aa3c4/gr1.jpg

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