Department of Chemistry, University College London, London, UK.
Chem Commun (Camb). 2018 Oct 2;54(79):11180-11183. doi: 10.1039/c8cc06556j.
Herein we report the transformation of readily synthesised acyl hydrazides into 2-hydrazobenzophenones via a novel molecular rearrangement pathway using aryne chemistry. The developed reaction protocol is performed under relatively mild conditions and is tolerant of a wide variety of functional groups, and the 2-hydrazobenzophenone products provide access to both 1H- and 2H-indazoles from a single intermediate.
在此，我们报告了一种通过芳炔化学将易于合成的酰腙转化为 2-酰基二苯甲酮的新型分子重排途径。所开发的反应方案在相对温和的条件下进行，并且对各种官能团具有耐受性，并且 2-酰基二苯甲酮产物可从单个中间体获得 1H-和 2H-吲唑。
