头颈部癌患者放疗前后对植物血凝素的淋巴细胞反应。
Lymphocyte response to phytohaemagglutinin before and after radiation therapy in patients with carcinomas of the head and neck.
作者信息
Stefani S S, Kerman R H
出版信息
J Laryngol Otol. 1977 Jul;91(7):605-9. doi: 10.1017/s0022215100084115.
PMID:302294
Abstract
The ability of peripheral blood lymphocytes to respond in vitro to phytohaemagglutinin (PHA) was studied before and after radiation therapy in patients with locally advanced squamous cell carcinomas of head and neck. Patient lymphocyte response to PHA was depressed before therapy and further declined following therapy. The pre-therapy PHA responsiveness was found to be prognostically significant in regard to patient survival.
摘要
对头颈部局部晚期鳞状细胞癌患者在放射治疗前后，研究了其外周血淋巴细胞在体外对植物血凝素（PHA）的反应能力。患者淋巴细胞对PHA的反应在治疗前降低，治疗后进一步下降。发现治疗前PHA反应性对患者生存具有预后意义。
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