Department of Radiology, LSU Health Sciences Center New Orleans, 1542 Tulane Avenue, New Orleans, LA, 70112, USA.
School of Medicine, LSU Health Sciences Center New Orleans, 1542 Tulane Avenue, New Orleans, LA, 70112, USA.
Abdom Radiol (NY). 2019 Feb;44(2):783-789. doi: 10.1007/s00261-018-1774-y.
To determine the feasibility of performing dual-energy CT with a single-source spectral detector system in obese patients.
Retrospective, IRB-approved review of 28 patients weighing ≥ 270 lbs (122 kg) who underwent CT of the abdomen on a single-source spectral detector system was performed. Two blinded, independent radiologists rated relative preference between conventional CT images taken at 120 kVp (CCT120) and monoenergetic 70 keV equivalent (MonoE70) as well as iodine map image quality in the spleen, pancreas, kidneys, and liver. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were compared between conventional CT and MonoE70 images and correlated with body habitus markers of weight, height, and abdominal diameter.
MonoE70 images were preferred by radiologists 100% of the time (1-sample t test, p < 0.0001) over conventional CCT120 images. Noise was significantly lower; SNR and CNR were significantly higher in MonoE70 images than in CCT120 images (paired t tests, p < 0.0001). Mean iodine map rating (scale 1-5) was 4.54 ± 0.58, denoting near homogenous and complete iodine mapping through the spleen, pancreas, kidneys, and liver for the majority of patients. Body habitus markers were not significantly correlated with image preference score; noise; MonoE70 SNR; MonoE70 CNR; change in noise, SNR, or CNR from CCT120 to MonoE70, or iodine map quality; ordinal and linear regression, p = 0.2547, p = 0.6837, p = 0.1888, p = 0.5489, p = 0.9830, p = 0.8849, p = 0.8741, p = 0.1522, respectively.
The single-source spectral detector implementation of dual-energy CT provides viable, high-quality imaging for obese patients.
确定在肥胖患者中使用单源能谱探测器系统进行双能 CT 的可行性。
回顾性分析了在单源能谱探测器系统上进行腹部 CT 检查的 28 例体重≥270 磅(122 公斤)的患者。两位盲法、独立的放射科医生对常规 120 kVp(CCT120)和单能量 70 keV 等效(MonoE70)图像以及脾脏、胰腺、肾脏和肝脏的碘图质量进行了相对偏好评分。比较常规 CT 与 MonoE70 图像的信噪比(SNR)和对比噪声比(CNR),并与体重、身高和腹围等身体形态标志物相关。
放射科医生 100%(1 样本 t 检验,p<0.0001)时间更喜欢 MonoE70 图像而不是常规 CCT120 图像。噪声显著降低;MonoE70 图像的 SNR 和 CNR 显著高于 CCT120 图像(配对 t 检验,p<0.0001)。平均碘图评分(1-5 级)为 4.54±0.58,表示大多数患者的脾脏、胰腺、肾脏和肝脏的碘分布均匀完整。身体形态标志物与图像偏好评分、噪声、MonoE70 SNR、MonoE70 CNR、从 CCT120 到 MonoE70 的噪声、SNR 或 CNR 变化、碘图质量均无显著相关性;有序和线性回归,p=0.2547,p=0.6837,p=0.1888,p=0.5489,p=0.9830,p=0.8849,p=0.8741,p=0.1522。
单源能谱探测器实现的双能 CT 可为肥胖患者提供可行的高质量成像。