Diagnostic Imaging Area, Catholic University of the Sacred Heart, Gemelli Foundation, School of Medicine, Rome, Italy.
Eur Rev Med Pharmacol Sci. 2018 Sep;22(17):5438-5446. doi: 10.26355/eurrev_201809_15803.
The purpose of this study is to verify the effectiveness and complications occurrence of radiofrequency ablation (RFA) in the treatment of osteoid osteoma (OO) in non-operating room anesthesia (N.O.R.A.).
From 2014 to 2017, 61 patients affected by OO (40 men and 21 women) with an age of 20.7 years on average (range, 4-51 years; 12 patients aged 20 years or younger) underwent computed tomography-guided percutaneous radiofrequency ablation (RFA) in N.O.R.A. (Non-Operating Room Anesthesia). Lesion sites treated were: femur (27), tibia (22), pelvis (2), talar bone (3), distal radius (1), and humerus (6). Mean follow-up time was 36 months. In each case, anesthesiologic support followed a new protocol (N.O.R.A. protocol), approved by our Institute. Primary success rate, complications, symptom-free intervals, and follow-up results were evaluated.
Pain relief (evaluated with Visual Analogue Scale - VAS) was significant in 97% of patients; it disappeared within 24 hours of the procedure in 44 patients, within 3 days in 10 patients, and within 7 days in 7 patients. After 6 months of observation time, 60 of 61 patients were successfully treated and had no more complaints. In 2 patients, two major complications were found: infection of the site treated, healed with antibiotics, and a nerve lesion, healed with steroid therapy. No other complications were observed.
RFA is a highly effective, efficient, minimally invasive and safe method for the treatment of OO following N.O.R.A.
本研究旨在验证非手术麻醉(N.O.R.A.)下射频消融(RFA)治疗骨样骨瘤(OO)的有效性和并发症发生率。
2014 年至 2017 年,61 例 OO 患者(40 名男性和 21 名女性)接受了计算机断层扫描引导下经皮射频消融(RFA)治疗,平均年龄 20.7 岁(范围 4-51 岁;12 名患者年龄在 20 岁或以下)。接受治疗的病变部位包括:股骨(27 例)、胫骨(22 例)、骨盆(2 例)、距骨(3 例)、桡骨远端(1 例)和肱骨(6 例)。平均随访时间为 36 个月。在每种情况下,麻醉支持遵循我们研究所批准的新方案(N.O.R.A. 方案)。评估了主要成功率、并发症、无症状间隔和随访结果。
97%的患者疼痛缓解明显(用视觉模拟评分法评估-VAS);44 例患者在手术 24 小时内疼痛消失,10 例患者在 3 天内,7 例患者在 7 天内。在 6 个月的观察时间内,61 例患者中的 60 例成功治疗且无更多抱怨。在 2 例患者中,发现了两种主要并发症:治疗部位感染,经抗生素治愈,神经损伤,经类固醇治疗治愈。未观察到其他并发症。
RFA 是一种高效、有效、微创且安全的治疗 N.O.R.A. 下 OO 的方法。