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在非手术室麻醉下用射频消融术治疗骨样骨瘤。骨样骨瘤消融治疗的一种不同方法。

Osteoid osteoma treated with radiofrequency ablation in non-operating room anesthesia. A different way of approaching ablative therapy on osteoid osteoma.

机构信息

Diagnostic Imaging Area, Catholic University of the Sacred Heart, Gemelli Foundation, School of Medicine, Rome, Italy.

出版信息

Eur Rev Med Pharmacol Sci. 2018 Sep;22(17):5438-5446. doi: 10.26355/eurrev_201809_15803.

Abstract

OBJECTIVE

The purpose of this study is to verify the effectiveness and complications occurrence of radiofrequency ablation (RFA) in the treatment of osteoid osteoma (OO) in non-operating room anesthesia (N.O.R.A.).

PATIENTS AND METHODS

From 2014 to 2017, 61 patients affected by OO (40 men and 21 women) with an age of 20.7 years on average (range, 4-51 years; 12 patients aged 20 years or younger) underwent computed tomography-guided percutaneous radiofrequency ablation (RFA) in N.O.R.A. (Non-Operating Room Anesthesia). Lesion sites treated were: femur (27), tibia (22), pelvis (2), talar bone (3), distal radius (1), and humerus (6). Mean follow-up time was 36 months. In each case, anesthesiologic support followed a new protocol (N.O.R.A. protocol), approved by our Institute. Primary success rate, complications, symptom-free intervals, and follow-up results were evaluated.

RESULTS

Pain relief (evaluated with Visual Analogue Scale - VAS) was significant in 97% of patients; it disappeared within 24 hours of the procedure in 44 patients, within 3 days in 10 patients, and within 7 days in 7 patients. After 6 months of observation time, 60 of 61 patients were successfully treated and had no more complaints. In 2 patients, two major complications were found: infection of the site treated, healed with antibiotics, and a nerve lesion, healed with steroid therapy. No other complications were observed.

CONCLUSIONS

RFA is a highly effective, efficient, minimally invasive and safe method for the treatment of OO following N.O.R.A.

摘要

目的

本研究旨在验证非手术麻醉(N.O.R.A.)下射频消融(RFA)治疗骨样骨瘤(OO)的有效性和并发症发生率。

患者与方法

2014 年至 2017 年,61 例 OO 患者(40 名男性和 21 名女性)接受了计算机断层扫描引导下经皮射频消融(RFA)治疗,平均年龄 20.7 岁(范围 4-51 岁;12 名患者年龄在 20 岁或以下)。接受治疗的病变部位包括:股骨(27 例)、胫骨(22 例)、骨盆(2 例)、距骨(3 例)、桡骨远端(1 例)和肱骨(6 例)。平均随访时间为 36 个月。在每种情况下,麻醉支持遵循我们研究所批准的新方案(N.O.R.A. 方案)。评估了主要成功率、并发症、无症状间隔和随访结果。

结果

97%的患者疼痛缓解明显(用视觉模拟评分法评估-VAS);44 例患者在手术 24 小时内疼痛消失,10 例患者在 3 天内,7 例患者在 7 天内。在 6 个月的观察时间内,61 例患者中的 60 例成功治疗且无更多抱怨。在 2 例患者中,发现了两种主要并发症:治疗部位感染,经抗生素治愈,神经损伤,经类固醇治疗治愈。未观察到其他并发症。

结论

RFA 是一种高效、有效、微创且安全的治疗 N.O.R.A. 下 OO 的方法。

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