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由松香引起的职业性过敏性接触性皮炎。

Occupational allergic contact dermatitis caused by colophonium.

机构信息

Occupational Medicine, Finnish Institute of Occupational Health (FIOH), Helsinki, Finland.

出版信息

Contact Dermatitis. 2019 Jan;80(1):9-17. doi: 10.1111/cod.13114. Epub 2018 Sep 19.

Abstract

BACKGROUND

Colophonium is a common contact allergen that is present not only in household products but also in occupational settings.

OBJECTIVES

To describe the sources of occupational exposure to colophonium and the occupations at risk of colophonium allergy.

METHODS

We reviewed patch test files from the years 2002 to 2017 at the Finnish Institute of Occupational Health for patients with allergic reactions to colophonium and abietic acid. We analysed the patch test, occupation and exposure data of 39 patients diagnosed with occupational allergic contact dermatitis (OACD) caused by colophonium.

RESULTS

Of the patients examined for suspected occupational dermatitis, 4.6% (n = 118) reacted positively to colophonium. The majority of the OACD patients worked in the wood industry, as machinists, or were involved in soldering or agriculture. The most common occupational sources of exposure were coniferous wood and wood-derived materials, followed by glues, metalworking fluids, and soldering materials. Colophonium is not always mentioned in safety data sheets (SDSs), and the sources of colophonium exposure are often materials for which there are no SDSs.

CONCLUSION

OACD caused by colophonium is quite common and occurs in a variety of occupations. SDSs provide poor information for exposure assessment. Patch testing with the patient's own materials was often useful in establishing the diagnosis.

摘要

背景

松香是一种常见的接触过敏原,不仅存在于家用产品中,也存在于职业环境中。

目的

描述松香职业接触的来源以及易患松香过敏的职业。

方法

我们回顾了 2002 年至 2017 年在芬兰职业健康研究所因松香和松香酸过敏而接受斑贴试验的患者的斑贴试验档案。我们分析了 39 例诊断为职业性过敏性接触性皮炎(OACD)的患者的斑贴试验、职业和暴露数据,这些患者的病因均为松香。

结果

在检查疑似职业性皮炎的患者中,4.6%(n=118)对松香呈阳性反应。大多数 OACD 患者从事木材加工业,如机械师,或从事焊接或农业工作。最常见的职业接触源是针叶木和木质材料,其次是胶水、金属加工液和焊接材料。松香并不总是在安全数据表(SDS)中提及,而且松香的接触源通常是没有 SDS 的材料。

结论

由松香引起的 OACD 相当常见,发生在多种职业中。SDS 提供的暴露评估信息很差。用患者自己的材料进行斑贴试验通常有助于确诊。

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