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癌症一级和二级预防的生活方式改变及政策影响:饮食、运动、防晒和减少饮酒

Lifestyle Modifications and Policy Implications for Primary and Secondary Cancer Prevention: Diet, Exercise, Sun Safety, and Alcohol Reduction.

作者信息

LoConte Noelle K, Gershenwald Jeffrey E, Thomson Cynthia A, Crane Tracy E, Harmon Gil E, Rechis Ruth

机构信息

From the Carbone Cancer Center and University of Wisconsin School of Medicine and Public Health, Madison, WI; Department of Surgical Oncology, Melanoma and Skin Center, The University of Texas MD Anderson Cancer Center, Houston, TX; Department of Health Promotion Sciences, Mel and Enid Zuckerman College of Public Health, University of Arizona Cancer Center, Tucson, AZ; Biobehavioral Health Sciences Division, College of Nursing, University of Arizona Cancer Center, Tucson, AZ; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI; Be Well Communities, Cancer Prevention and Control Platform, The University of Texas MD Anderson Cancer Center, Houston, TX.

出版信息

Am Soc Clin Oncol Educ Book. 2018 May 23;38:88-100. doi: 10.1200/EDBK_200093.

Abstract

Improved cancer treatments and cancer detection methods are not likely to completely eradicate the burden of cancer. Primary prevention of cancer is a logical strategy to use to control cancer while also seeking novel treatments and earlier detection. Lifestyle modification strategies to improve primary prevention and risk reduction for the development of cancer include choosing a healthy diet with an emphasis on plant sources, maintaining a healthy weight throughout life, being physically active, regularly using sunscreen and wearing protective clothing, limiting sun exposure during the hours of 10 AM to 2 PM, avoiding indoor tanning, and reducing or eliminating alcohol use. In addition to continued use of ongoing education of the public, health care providers, and cancer support communities, other policy and public health efforts should be pursued as well. Examples of supported and successful policy approaches are included in this article, including efforts to limit indoor tanning and improve community-wide interventions to reduce ultraviolet radiation exposure as well as to formally support various alcohol policy strategies including increasing alcohol taxes, reducing alcohol outlet density, improving clinical screening for alcohol use disorders, and limiting youth exposure to alcohol marketing and advertising. These prevention strategies are expected to have the largest impact on the development of melanoma as well as breast, colorectal, head and neck, liver, and esophageal cancers. The impact of these strategies as secondary prevention is less well understood. Areas of additional needed research and implementation are also highlighted. Future areas of needed research are the effects of these modifications after the diagnosis of cancer (as secondary prevention).

摘要

改进的癌症治疗方法和癌症检测方法不太可能完全消除癌症负担。癌症的一级预防是一种合理的策略,可用于控制癌症,同时寻求新的治疗方法和更早的检测。改善癌症一级预防和降低癌症发生风险的生活方式改变策略包括选择以植物性食物为主的健康饮食、终生保持健康体重、积极锻炼身体、定期使用防晒霜并穿着防护服、在上午10点至下午2点之间限制阳光照射、避免室内晒黑以及减少或戒酒。除了持续对公众、医疗保健提供者和癌症支持社区进行教育外,还应采取其他政策和公共卫生措施。本文列举了一些得到支持且成功的政策方法,包括限制室内晒黑的努力、改善全社区减少紫外线辐射暴露的干预措施,以及正式支持各种酒精政策策略,包括提高酒精税、降低酒精销售点密度、改善酒精使用障碍的临床筛查,以及限制青少年接触酒精营销和广告。这些预防策略预计对黑色素瘤以及乳腺癌、结直肠癌、头颈癌、肝癌和食管癌的发生影响最大。这些策略作为二级预防的影响尚不太清楚。还强调了需要进一步研究和实施的领域。未来需要研究的领域是这些改变在癌症诊断后的效果(作为二级预防)。

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