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基于生活方式的癌症预防与治疗。

Cancer Prevention and Treatment Based on Lifestyles.

机构信息

Department of Biological Sciences, National University of Medical Sciences, Rawalpindi, Pakistan.

School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, USA.

出版信息

Cancer Treat Res. 2024;191:245-279. doi: 10.1007/978-3-031-55622-7_10.

Abstract

Cancer morbidity and mortality incidence are rapidly increasing over the period of time. Cancer prevention, alongside innovative therapies and earlier detection, is considered a key strategy for reducing the overall cancer burden. Substantial evidence indicates a clear correlation between lifestyle factors and changes in nutrient metabolism. Approximately 5-10% of all cancer cases are attributed to genetic factors, whereas 90-95% are due to environmental and lifestyle factors, suggesting that lifestyle interventions have significant prospects for preventing various cancers. Healthy lifestyle changes, in particular healthy diets, physical activity, staying at a healthy weight, reduction or elimination of tobacco/alcohol consumption, and avoiding exposure to radiation and other carcinogens, are significant factors to be considered to tackle the challenges associated with cancer in modern society. This chapter aims to provide lifestyle intervention strategies to improve cancer prevention and risk reduction while promoting the health of cancer patients. The therapeutic role of some dietary regimens and supplements, as well as complementary and alternative health approaches, in cancer treatment is also discussed.

摘要

癌症发病率和死亡率在一段时间内迅速上升。癌症预防,以及创新的治疗方法和早期检测,被认为是降低整体癌症负担的关键策略。大量证据表明,生活方式因素与营养代谢变化之间存在明显的相关性。大约 5-10%的癌症病例归因于遗传因素,而 90-95%的癌症是由于环境和生活方式因素引起的,这表明生活方式干预在预防各种癌症方面具有广阔的前景。健康的生活方式改变,特别是健康饮食、身体活动、保持健康体重、减少或戒除烟草/酒精消费,以及避免接触辐射和其他致癌物质,是应对现代社会癌症相关挑战的重要因素。本章旨在提供生活方式干预策略,以改善癌症预防和降低风险,同时促进癌症患者的健康。一些饮食方案和补充剂以及补充和替代健康方法在癌症治疗中的治疗作用也将进行讨论。

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