Antuono Latronico, Angela Faggian, Luca Nicosia, Giovanni Mazzarol, Enrico Cassano
IEO, European Institute of Oncology IRCCS, Breast Imaging Unit, Via G. Ripamonti, 435, 20141, Milan, Italy.
Postgraduate School of Radiology, Università degli Studi di Milano, Milan, Via Festa del Perdono 7, Milan, Italy.
Radiol Case Rep. 2018 Sep 13;13(6):1166-1169. doi: 10.1016/j.radcr.2018.08.008. eCollection 2018 Dec.
Breast metastasis from ovarian cancer is a rare event, with vary clinical and imaging presentations, depends on the form of dissemination of the disease and may mimic primary benign and malignant lesions.Confirmation of the diagnosis is of pivotal importance to choice an adequate therapeutic planning, allowing to avoid unnecessary surgeries and to provide appropriate systemic therapy. In this manuscript, we present a case of breast metastasis from ovarian cancer. The patient presented to our Institute with a localized, palpable mass in the upper outer quadrant of the right breast. Mammography and breast sonography showed a singular, round, and homogenous mass with regular borders. No suspicious axillary node was observed. Lesion biopsy revealed the presence of epithelial malignant tumor cells, compatible with a tube-ovarian serous histotype. So, although it could be rare, secondary malignant neoplasm should be considered in the differential diagnosis of breast lesions in patients with a personal history of ovarian cancer.
卵巢癌发生乳腺转移是一种罕见情况,其临床和影像学表现各异,取决于疾病的播散形式,且可能类似原发性良性和恶性病变。确诊对于选择恰当的治疗方案至关重要,有助于避免不必要的手术并提供合适的全身治疗。在本手稿中,我们呈现了一例卵巢癌乳腺转移病例。该患者因右乳外上象限出现一个可触及的局限性肿块前来我院就诊。乳腺钼靶和超声检查显示为一个单一的、圆形且均匀的肿块,边界规则。未观察到可疑腋窝淋巴结。病变活检显示存在上皮性恶性肿瘤细胞,符合输卵管 - 卵巢浆液性组织学类型。所以,尽管可能罕见,但对于有卵巢癌个人史的患者,在乳腺病变的鉴别诊断中应考虑继发性恶性肿瘤。