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妊娠剧吐所致韦尼克脑病:一例报告

Wernicke Encephalopathy Due to Hyperemesis Gravidarum in Pregnancy: A Case Report.

作者信息

Talib Vikash, Sultana Shazia, Hamad Ahmed, Yaqoob Uzair

机构信息

Accident & Emergency, Jinnah Sindh Medical University (SMC), Karachi, PAK.

Obstetrics and Gynecology, Ziauddin University, Karachi, PAK.

出版信息

Cureus. 2018 Jul 17;10(7):e2991. doi: 10.7759/cureus.2991.

DOI:10.7759/cureus.2991
PMID:30237950
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6141217/
Abstract

Wernicke's encephalopathy (WE) is a life-threatening acute or sub-acute neurological emergency characterized by ataxia, confusion, nystagmus, and ophthalmoparesis caused by thiamine deficiency. It was first described in 1881 by Carl Wernicke with alcohol being the most common cause. We present a rare case of a 35-year-old pregnant female who presented to our emergency department with a history of vomiting and loose motions for two weeks. She later developed fever, confusion, slurred speech and blurring of vision. Magnetic resonance imaging (MRI) of the brain revealed typical lesions of WE. She was immediately treated with thiamine and her symptoms improved in a few days.

摘要

韦尼克脑病(WE)是一种危及生命的急性或亚急性神经急症,其特征为共济失调、意识模糊、眼球震颤及眼肌麻痹,由硫胺素缺乏引起。该病于1881年由卡尔·韦尼克首次描述,最常见的病因是酒精。我们报告一例罕见病例,一名35岁的孕妇因呕吐和腹泻两周就诊于我们的急诊科。她后来出现发热、意识模糊、言语不清和视力模糊。脑部磁共振成像(MRI)显示出典型的韦尼克脑病病变。她立即接受了硫胺素治疗,几天后症状有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/752d/6141217/dc7d14273ec7/cureus-0010-00000002991-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/752d/6141217/dc7d14273ec7/cureus-0010-00000002991-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/752d/6141217/dc7d14273ec7/cureus-0010-00000002991-i01.jpg

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Wernicke encephalopathy in a patient after liver transplantation: A case report.肝移植后患者出现韦尼克脑病:病例报告。
World J Gastroenterol. 2017 Dec 21;23(47):8432-8436. doi: 10.3748/wjg.v23.i47.8432.
2
Wernicke's encephalopathy with chorea: Neuroimaging findings.伴有舞蹈症的韦尼克脑病:神经影像学表现
Dement Neuropsychol. 2016 Oct-Dec;10(4):370-372. doi: 10.1590/s1980-5764-2016dn1004020.
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A case report: Non-alcoholic Wernicke encephalopathy associated with polyneuropathy.病例报告:与多发性神经病相关的非酒精性韦尼克脑病
J Int Med Res. 2017 Dec;45(6):1794-1801. doi: 10.1177/0300060517699039. Epub 2017 Apr 3.
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Wernicke's encephalopathy due to hyperemesis gravidarum: Clinical and magnetic resonance imaging characteristics.妊娠剧吐所致韦尼克脑病:临床及磁共振成像特征
J Postgrad Med. 2016 Oct-Dec;62(4):260-263. doi: 10.4103/0022-3859.191005.
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Bilateral Blindness Following Chemoradiation for Locally Advanced Oropharyngeal Carcinoma.局部晚期口咽癌放化疗后双侧失明
Cureus. 2015 Oct 15;7(10):e352. doi: 10.7759/cureus.352.
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Wernicke's encephalopathy following Hyperemesis gravidarum. A report of three cases.妊娠剧吐后韦尼克脑病。三例报告。
Neuroradiol J. 2013 Feb;26(1):35-40. doi: 10.1177/197140091302600106. Epub 2013 Mar 8.
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Wernicke's encephalopathy induced by hyperemesis gravidarum.妊娠剧吐所致韦尼克脑病
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