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妊娠剧吐所致韦尼克脑病

Wernicke's encephalopathy induced by hyperemesis gravidarum.

作者信息

Palacios-Marqués Ana, Delgado-García Silvia, Martín-Bayón Tina, Martínez-Escoriza Juan Carlos

机构信息

Obstetrics and Gynaecology Department, University General Hospital of Alicante, Alicante, Spain.

出版信息

BMJ Case Rep. 2012 Jun 8;2012:bcr2012006216. doi: 10.1136/bcr-2012-006216.

Abstract

Wernicke's encephalopathy (WE) is a reversible neurological emergency caused by thiamine deficiency. Prolonged vomiting in pregnancy results in thiamine depletion. The early recognition of its clinical signs and symptoms is essential to establish the suspected diagnosis and can be confirmed by MRI. Prompt administration of thiamine is important for preventing the occurrence of sequelae in the mother and for improving the fetal prognostic. We report a case of WE induced by hyperemesis gravidarum with a good maternal and fetal outcome.

摘要

韦尼克脑病(WE)是一种由硫胺素缺乏引起的可逆性神经急症。妊娠期长期呕吐会导致硫胺素缺乏。早期识别其临床体征和症状对于建立疑似诊断至关重要,且可通过磁共振成像(MRI)确诊。及时给予硫胺素对于预防母亲出现后遗症以及改善胎儿预后很重要。我们报告一例由妊娠剧吐诱发的韦尼克脑病病例,母婴结局良好。

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Commentary.评论
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本文引用的文献

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Wernicke's encephalopathy complicating hyperemesis gravidarum: from the background to the present.妊娠剧吐并发韦尼克脑病:从背景到现状
J Matern Fetal Neonatal Med. 2012 Aug;25(8):1499-504. doi: 10.3109/14767058.2011.629253. Epub 2011 Nov 4.
2
Neurological complications in hyperemesis gravidarum.妊娠剧吐的神经系统并发症。
Neurol Sci. 2012 Feb;33(1):133-5. doi: 10.1007/s10072-011-0660-y. Epub 2011 Jul 1.
5
Wernicke encephalopathy complicating hyperemesis gravidarum: a case report.妊娠剧吐并发韦尼克脑病:一例报告
Eur J Obstet Gynecol Reprod Biol. 2010 Mar;149(1):118-9. doi: 10.1016/j.ejogrb.2009.10.018. Epub 2009 Nov 13.
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Wernicke's encephalopathy: beyond alcoholism.韦尼克脑病:超越酒精中毒
Nat Clin Pract Neurol. 2006 Jan;2(1):54-8; quiz 58. doi: 10.1038/ncpneuro0094.
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Wernicke's encephalopathy with hyperemesis and ketoacidosis.伴有剧烈呕吐和酮症酸中毒的韦尼克脑病
Obstet Gynecol. 2006 Feb;107(2 Pt 2):486-90. doi: 10.1097/01.AOG.0000172373.41828.8a.

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