Rumpik David, Rumpikova Tatana, Pohanka Michal, Ventruba Pavel, Belaskova Silvie
Clinic of Reproductive Medicine and Gynecology Zlin, Zlin, Czech Republic.
Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry, Masaryk University Brno, Brno, Czech Republic.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2019 Jun;163(2):155-160. doi: 10.5507/bp.2018.040. Epub 2018 Sep 20.
Gestational surrogacy, is a treatment option for women with certain clearly defined medical problems, usually an absent uterus, to help them have their own genetic children. The aim of our study was to review, evaluate and share our experience and outcomes over the last 13 years of the largest surrogacy program in the Czech republic.
A total of 75 intended mothers and 82 surrogate mothers participated in this study. A retrospective cohort study was performed. Anonymized data were collected on 130 cycles of gestational surrogate (2004-2017) directly from the Clinic database.
We performed 130 in vitro fertilization cycles with gestational surrogacy which involved 73 fresh embryo transfers and 57 frozen embryo transfers. We achieved 57 (43.9%) pregnancies and 42 (32.3%) live births. The rate of multiple pregnancies was only 2.3 %. The most common indication for using was an absent or damaged uterus (65%), followed by medical conditions precluding pregnancy (23%) and repeated in vitro fertilization cycles or pregnancy failure (12%).
In the 14 years of our experience, we have shown that treatment of young women with specific indications for gestational surrogacy is beneficial, successful and relatively free of complications. However, it is imperative to follow the medical indications for this treatment and specialist recommendations.
妊娠代孕是针对患有某些明确界定的医学问题（通常是子宫缺失）的女性的一种治疗选择，以帮助她们拥有自己的亲生孩子。我们研究的目的是回顾、评估并分享我们在过去13年里于捷克共和国最大的代孕项目中的经验和成果。
共有75位意向母亲和82位代孕母亲参与了本研究。进行了一项回顾性队列研究。直接从诊所数据库收集了130个妊娠代孕周期（2004 - 2017年）的匿名数据。
我们进行了130个妊娠代孕的体外受精周期，其中包括73次新鲜胚胎移植和57次冷冻胚胎移植。我们实现了57例（43.9%）妊娠和42例（32.3%）活产。多胎妊娠率仅为2.3%。使用代孕最常见的指征是子宫缺失或受损（65%），其次是妊娠禁忌的医学状况（23%）以及反复体外受精周期或妊娠失败（12%）。
在我们14年的经验中，我们表明对有特定妊娠代孕指征的年轻女性进行治疗是有益、成功且相对无并发症的。然而，必须遵循这种治疗的医学指征和专家建议。
