UCHealth-Anschutz Medical Campus, University of Colorado Hospital, Aurora, CO.
Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO.
Acad Emerg Med. 2019 Jun;26(6):639-647. doi: 10.1111/acem.13620. Epub 2018 Oct 25.
The Emergency Medicine Specimen Bank (EMSB) was developed to facilitate precision medicine in acute care. The EMSB is a biorepository of clinical health data and biospecimens collected from all adult English- or Spanish-speaking individuals who are able and willing to provide consent and are treated at the UCHealth-University of Colorado Hospital Emergency Department. The EMSB is the first acute care biobank that seeks to enroll all patients, with all conditions who present to the ED. Acute care biobanking presents many challenges that are unique to acute care settings such as providing informed consent in a uniquely stressful and fast-paced environment and collecting, processing, and storing samples for tens of thousands of patients per year. Here, we describe the process by which the EMSB overcame these challenges and was integrated into clinical workflow allowing for operation 24 hours a day, 7 days a week at a reasonable cost. Other institutions can implement this template, further increasing the power of biobanking research to inform treatment strategies and interventions for common and uncommon phenotypes in acute care settings.
急诊医学标本库（EMSB）的建立旨在促进急症护理中的精准医学。EMSB 是一个临床健康数据和生物标本的生物库，这些数据和标本是从所有能够并愿意提供同意书并在 UCHealth-科罗拉多大学医院急诊部接受治疗的讲英语或西班牙语的成年个体中收集而来的。EMSB 是第一个急性护理生物库，旨在招募所有到急诊就诊的患者，无论其病情如何。急性护理生物库提出了许多挑战，这些挑战是急性护理环境所特有的，例如在独特的紧张和快节奏的环境中提供知情同意，以及每年为数以万计的患者收集、处理和储存样本。在这里，我们描述了 EMSB 如何克服这些挑战并整合到临床工作流程中的过程，使其能够以合理的成本每天 24 小时、每周 7 天运行。其他机构可以实施这一模板，进一步增强生物库研究的力量，以为急性护理环境中的常见和罕见表型提供治疗策略和干预措施的信息。
