Bousfiha B, Ghazzar F Z, Slaoui B, Ladner J, Hamza M
Odontostomatol Trop. 2016 Dec;39(156):49-56.
The aim of the study was to investigate oral health in asthmatic children using inhaled therapy and to compare the oral health status according to β2 agonist and corticosteroid dose administrated.
The study group composed of 160 children aged between 2 and 15 years old who had bronchial asthma at different degrees of severity, the children followed at university hospital of Casablanca. A questionnaire was filled referring to oral health habits. For dental examinations, world health organization criteria and for plaque indices the Silness and Löe plaque index were used. Oral mucosal was examined to detect candidiasis or ulcerations.
The dental plaque registered was 1,13 ± 0,64. The mean DMFT was 3,75 ± 1,53 and the mean DMFT was 5,50 ± 3,02. A statistically significant higher average DMFT and DMFT values were observed with higher dose of β2 agonist (p < 0,05). Almost a third of studied population had oral candidiasis and 6,9% had ulcerations. These oral mucosal lesions were particularly observed in children receiving inhaled corticosteroid higher than 400 µg/j (P < 10-5) and they were lower in children using a spacer device and rinsing the mouth after treatment (P < 10-5).
The results suggest higher caries susceptibility and oral mucosal lesions among asthmatic children undergoing inhaled treatment with β2 agonist and corticosteroid. A special attention by doctors and health professionals of these patients is necessary and asthmatic children are recommended to adopt more precautionary oral hygiene practices.
本研究旨在调查使用吸入疗法的哮喘儿童的口腔健康状况,并根据β2激动剂和皮质类固醇的给药剂量比较口腔健康状况。
研究组由160名年龄在2至15岁之间、患有不同严重程度支气管哮喘的儿童组成,这些儿童在卡萨布兰卡大学医院接受随访。填写了一份关于口腔健康习惯的问卷。牙科检查采用世界卫生组织标准,牙菌斑指数采用Silness和Löe菌斑指数。检查口腔黏膜以检测念珠菌病或溃疡。
记录的牙菌斑评分为1.13±0.64。平均龋失补牙面数(DMFT)为3.75±1.53,平均龋补牙面数(dmft)为5.50±3.02。β2激动剂剂量越高,平均DMFT和dmft值在统计学上显著更高(p<0.05)。近三分之一的研究人群患有口腔念珠菌病,6.9%患有溃疡。这些口腔黏膜病变在接受高于400μg/天吸入皮质类固醇的儿童中尤为明显(P<10-5),而在使用储物罐装置并在治疗后漱口的儿童中则较低(P<10-5)。
结果表明,接受β2激动剂和皮质类固醇吸入治疗的哮喘儿童患龋齿的易感性和口腔黏膜病变较高。这些患者的医生和健康专业人员有必要给予特别关注,建议哮喘儿童采取更多预防性口腔卫生措施。